ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2020
Frontal Alpha Asymmetry Moderated by Suicidal Ideation in Patients with Major Depressive Disorder: A Comparison with Healthy Individuals.
Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Resting-state EEG activity in depression: a systematic review and meta-analysis.NeuroImage. Clinical · 2026Pooled it
- Association of resting-state EEG with suicidality in depressed patients: a systematic review.BMC psychiatry · 2025Pooled it
- The relationship between emotional regulation and hemispheric lateralization in depression: a systematic review and a meta-analysis.Translational psychiatry · 2022Pooled it
- Patterns of Lateral Frontal Delta Asymmetry in Adult Attention-deficit/Hyperactivity Disorder with Comorbid Depression: A Quantitative Electroencephalography Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- Lymphocyte subpopulations and EEG asymmetry.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Alpha-band fronto-limbic hyperconnectivity in adolescents with major depression and suicidal ideation.BMC psychiatry · 2026Article
- Uncovering oscillatory dysregulation associated with suicide risk in major depressive disorder: a narrative review.Translational psychiatry · 2026Review
- Review
- EEG Biomarkers for a Precision-Medicine Approach to Noninvasive Brain Stimulation for Major Depressive Disorder.Research square · 2025Article
- Association of Hemispheric Asymmetry of Dopamine-Transporter Binding with Risk of Parkinsonian Depression.Movement disorders clinical practice · 2025Article
- Meta analysis of resting frontal alpha asymmetry as a biomarker of depression.Npj mental health research · 2025Article
- Alpha oscillatory dysregulation: mapping EEG oscillatory in suicidal depression.Frontiers in human neuroscience · 2025Article
- Quantitative and qualitative electroencephalography in the diagnosis and monitoring of depression. A modern approach to clinical neurophysiology.Frontiers in human neuroscience · 2025Review
- Frontal Alpha Asymmetry and Its Modulation by Monoaminergic Neurotransmitters in Depression.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Review
- Differences in Electroencephalography Power and Asymmetry at Frontal Region in Young Adults with Attention-deficit/hyperactivity Disorder: A Quantitative Electroencephalography Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- The Relationship between Depression Severity and Prefrontal Hemodynamic Changes in Adolescents with Major Depression Disorder: A Functional Near-infrared Spectroscopy Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- Clinical Implication of Maumgyeol Basic Service-the 2 Channel Electroencephalography and a Photoplethysmogram-based Mental Health Evaluation Software.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- The Link between Suicidality and Electroencephalography Asymmetry: A Systematic Review and Meta-analysis.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Review
- A resting state EEG study on depressed persons with suicidal ideation.IBRO neuroscience reports · 2023Article
- Resting State EEG Correlates of Suicide Ideation and Suicide Attempt.Journal of personalized medicine · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveFrontal alpha asymmetry (FAA) of electroencephalography (EEG) has been studied to differentiate patients with major depressive disorder (MDD) from healthy controls (HC). However, inconsistent results have been obtained thus far. Suicidal ideation (SI) has been known to alter frontal lobe activity, and could be an important covariate in FAA studies. This study aimed to explore the influence of FAA on the relationship among MDD patients with SI and without SI, and HC.
methodsSixty-seven patients with MDD (44 without and 23 with SI) and 60 HCs were recruited. Resting state EEG was recorded with their eyes open, and FAA as a lateralized index of alpha power was calculated in the frontal brain region. Hamilton Rating Scale for Anxiety and Depression scores were estimated.
resultsFAA was higher (increased alpha power in the left frontal region) in the MDD group than in the HC group. The FAA was lower (reduced alpha power in the left frontal region) in MDD patients with SI than in MDD patients without SI. The severity of depression and anxiety symptoms were significantly correlated with FAA only in MDD patients with SI. SI moderated the effects of depressive symptom on FAA in the MDD group.
conclusionOur results suggest that SI is a clinically important moderator of frontal alpha asymmetry in patients with MDD.
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