Evidence map›Paper›PMID 31958774›Full record

ArticleAging2020

Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs.

Ying-Jie Niu, Wenjun Zhou, Zheng-Wen Nie, Dongjie Zhou, Yong-Nan Xu, Sun A Ock, Chang-Guo Yan, Xiang-Shun Cui

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Exploring the protective effects of coenzyme Q10 on female fertility.Frontiers in cell and developmental biology · 2025
    Review
  10. Article
  11. The role of CoQ10 in embryonic development.Journal of assisted reproduction and genetics · 2024
    Review
  12. Review
  13. Article
  14. Coenzyme Q10 Stimulate Reproductive Vatality.Drug design, development and therapy · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Mitochondria: emerging therapeutic strategies for oocyte rescue.Reproductive sciences (Thousand Oaks, Calif.) · 2022
    Review
  20. Quercetin protects porcine oocytes fromFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ying-Jie NiuDepartment of Animal Science, Chungbuk National University, Cheongju, South Korea.
Wenjun ZhouDepartment of Animal Science, Chungbuk National University, Cheongju, South Korea.
Zheng-Wen NieDepartment of Animal Science, Chungbuk National University, Cheongju, South Korea.
Dongjie ZhouDepartment of Animal Science, Chungbuk National University, Cheongju, South Korea.
Yong-Nan XuCollege of Agriculture, Yanbian University, Yanji, China.
Sun A OckAnimal Biotechnology Division, National Institute of Animal Science, Rural Development Administration, Jeonju, South Korea.
Chang-Guo YanCollege of Agriculture, Yanbian University, Yanji, China.
Xiang-Shun CuiDepartment of Animal Science, Chungbuk National University, Cheongju, South Korea.
Chungbuk National University · KRRural Development Administration · KRYanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ubiquinol-10, the reduced form of coenzyme Q10, protects mammalian cells from oxidative damage and enhances mitochondrial activity. However, the protective effect of ubiquinol-10 on mammalian oocytes is not well understood. In this study, we investigated the effect of ubiquinol-10 on porcine oocytes during postovulatory aging. Metaphase II oocytes were selected as fresh oocytes and further cultured for 48 h with different concentrations of ubiquinol-10 (0-400 μM)

Indexed as

AgingAnimalsApoptosisCellular SenescenceEmbryonic DevelopmentMitochondriaMitophagyOocytesOvulationOxidative StressReactive Oxygen SpeciesSwineUbiquinoneReactive Oxygen Speciesubiquinol-10Ubiquinonemitochondriaoxidative stresspigpostovulatory agingubiquinol-10

Identifiers

PMID31958774
PMCPMC7053629
OpenAlexW3002069679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.