Evidence map›Paper›PMID 31958320›Full record

ArticleAging2020

Fibroblast growth factor 10 alleviates particulate matter-induced lung injury by inhibiting the HMGB1-TLR4 pathway.

Lingjing Liu, Chenjian Song, Jingli Li, Qiang Wang, Mingyang Zhu, Yiran Hu, Junjie Chen, Chaolei Chen, Jin-San Zhang, Nian Dong and 1 more

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway.Investigative ophthalmology & visual science · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lingjing LiuDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Chenjian SongDepartment of Pulmonary Medicine, Yiwu Central Hospital, Yiwu 322000, China.
Jingli LiDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Qiang WangDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Mingyang ZhuDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Yiran HuDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Junjie ChenDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Chaolei ChenDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Jin-San ZhangDepartment of Pharmacy, Wenzhou Medical University Pharmacy School, Wenzhou 325006, China.
Nian DongDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
Chengshui ChenDepartment of Pulmonary Medicine, Wenzhou Medical University First Affiliated Hospital, Wenzhou 325006, China.
First Affiliated Hospital of Wenzhou Medical University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to particulate matter (PM) is associated with increased incidence of respiratory diseases. The present study aimed to investigate the roles of fibroblast growth factor 10 (FGF10) in PM-induced lung injury. Mice were intratracheally instilled with FGF10 or phosphate-buffered saline at one hour before instillation of PM for two consecutive days. In addition, the anti-inflammatory impact of FGF10

Indexed as

BiomarkersBiopsyCell DeathCytokinesDisease SusceptibilityFibroblast Growth Factor 10Gene ExpressionGene Knockdown TechniquesHMGB1 ProteinHumansImmunohistochemistryLung InjuryParticulate MatterRespiratory MucosaSignal TransductionToll-Like Receptor 4BiomarkersCytokinesFibroblast Growth Factor 10HMGB1 ProteinParticulate MatterTLR4 protein, humanToll-Like Receptor 4FGF10HMGB1inflammationlung injuryparticulate matterTLR4

Identifiers

PMID31958320
PMCPMC7053597
OpenAlexW3002983941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.