Evidence map›Paper›PMID 31958208›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.

Sharad I Wadhwani, Andrew F Beck, John Bucuvalas, Laura Gottlieb, Uma Kotagal, Jennifer C Lai

Open access · bronzeAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Remote intervention engagement and outcomes in the Clinical Trials in Organ Transplantation in Children consortium multisite trial.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Trial
  4. Material economic hardships are associated with second-year hospitalizations after pediatric liver transplantation: Results from the SOCIAL-Tx study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Coproducing a health advocate intervention for pediatric liver transplant recipients using a human-centered design.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025
    Article
  9. Material economic hardships are associated with adverse 1-year outcomes after pediatric liver transplantation: Prospective cohort results from the multicenter SOCIAL-Tx Study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025
    Observational
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Where you live matters: Area deprivation predicts poor survival and liver transplant waitlisting.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  17. Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Observational
  18. Association of state Medicaid expansion policies with pediatric liver transplant outcomes.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sharad I WadhwaniUniversity of California San Francisco, San Francisco, California.ORCID 0000-0001-5565-6670
Andrew F BeckCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
John BucuvalasIcahn School of Medicine at Mount Sinai, New York, New York.
Laura GottliebUniversity of California San Francisco, San Francisco, California.
Uma KotagalCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Jennifer C LaiUniversity of California San Francisco, San Francisco, California.ORCID 0000-0003-2092-6380
University of California, San Francisco · USCincinnati Children's Hospital Medical Center · USIcahn School of Medicine at Mount Sinai · US

Funding

PEDIATRIC GASTROENTEROLOGY AND NUTRITION TRAINING GRANTT32DK007727 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Phillip P Minar · 1995 to 2026
$11.3M
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationR01AG059183 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer C. Lai · 2018 to 2026
$9.9M
Inpatient Asthma Care for Children: Adding a Place-Based, Community-Focused ApproK23AI112916 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI BECK, ANDREW FINKEL · 2014 to 2018
$721k
Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantationR21AG067554 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAI, JENNIFER C. · 2020 to 2021
$444k
NIAID NIH HHS K23 AI112916NIA NIH HHS R01 AG059183NIA NIH HHS R21 AG067554NIDDK NIH HHS T32 DK007727
6 · The paper itself

Abstract

Long-term outcomes remain suboptimal following pediatric liver transplantation; only one third of children have normal biochemical liver function without immunosuppressant comorbidities 10 years posttransplant. We examined the association between an index of neighborhood socioeconomic deprivation with graft and patient survival using the Scientific Registry of Transplant Recipients. We included children <19 years who underwent liver transplantation between January 1, 2008 to December 31, 2013 (n = 2868). Primary exposure was a neighborhood socioeconomic deprivation index-linked via patient home ZIP code-with a range of 0-1 (values nearing 1 indicate neighborhoods with greater socioeconomic deprivation). Primary outcome measures were graft failure and death, censored at 10 years posttransplant. We modeled survival using Cox proportional hazards. In univariable analysis, each 0.1 increase in the deprivation index was associated with a 14.3% (95% confidence interval [CI]): 3.8%-25.8%) increased hazard of graft failure and a 12.5% (95% CI: 2.5%-23.6%) increased hazard of death. In multivariable analysis adjusted for race, each 0.1 increase in the deprivation index was associated with a 11.5% (95% CI: 1.6%-23.9%) increased hazard of graft failure and a 9.6% (95% CI: -0.04% to 20.7%) increased hazard of death. Children from high deprivation neighborhoods have diminished graft and patient survival following liver transplantation. Greater attention to neighborhood context may result in improved outcomes for children following liver transplantation.

Indexed as

Graft SurvivalLiver TransplantationChildHumansProportional Hazards ModelsResidence CharacteristicsRisk FactorsSocioeconomic FactorsTreatment Outcomeclinical research/practiceethnicity/racegraft survivalhealth services and outcomes researchinsuranceliver transplantation/hepatologypatient survivalpediatricsScientific Registry for Transplant Recipients (SRTR)social sciences

Identifiers

PMID31958208
PMCPMC7261648
OpenAlexW3000909210

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.