Evidence map›Paper›PMID 31958060›Full record

ArticleeLife2020

Loss of centromere function drives karyotype evolution in closely related

Sundar Ram Sankaranarayanan, Giuseppe Ianiri, Marco A Coelho, Md Hashim Reza, Bhagya C Thimmappa, Promit Ganguly, Rakesh Netha Vadnala, Sheng Sun, Rahul Siddharthan, Christian Tellgren-Roth and 3 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Fungi as models of centromere innovation: from DNA sequence to 3-dimensional arrangement.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  8. Article
  9. Retracing the evolution ofMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Comparative genomics ofbioRxiv : the preprint server for biology · 2024
    Article
  15. Review
  16. Frequent transitions in mating-type locus chromosomal organization inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Review
  19. Frequent transitions in mating-type locus chromosomal organization inbioRxiv : the preprint server for biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Sundar Ram SankaranarayananMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India.
Giuseppe IaniriDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.ORCID 0000-0002-3278-8678
Marco A CoelhoDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.
Md Hashim RezaMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India.
Bhagya C ThimmappaMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India.
Promit GangulyMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India.
Rakesh Netha VadnalaThe Institute of Mathematical Sciences/HBNI, Chennai, India.
Sheng SunDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.
Rahul SiddharthanThe Institute of Mathematical Sciences/HBNI, Chennai, India.ORCID 0000-0002-2233-0954
Christian Tellgren-RothNational Genomics Infrastructure, Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Thomas L DawsonSkin Research Institute Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.
Kaustuv SanyalMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India.ORCID 0000-0002-6611-4073
Jawaharlal Nehru Centre for Advanced Scientific Research · INDuke University · USInstitute of Mathematical Sciences · INAgency for Science, Technology and Research · SGUppsala University · SE

Funding

Structure, function, and evolution of the Cryptococcus MAT locusR01AI050113 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2002 to 2024
$8.5M
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITINGR01AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 1997 to 2025
$6.7M
Genetics of Cryptococcus sexual reproductionR37AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2011 to 2020
$4.9M
NIAID NIH HHS R01 AI039115NIAID NIH HHS R01 AI050113NIAID NIH HHS R37 AI039115
6 · The paper itself

Abstract

Genomic rearrangements associated with speciation often result in variation in chromosome number among closely related species.

Indexed as

CentromereEvolution, MolecularKaryotypingChromosomes, FungalMalasseziaSpecies Specificitychromosome fusiondicentricdouble-strand breaksgeneticsgenomicskinetochoreskin microbe

Identifiers

PMID31958060
PMCPMC7025860
OpenAlexW3001294737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.