Evidence map›Paper›PMID 31958059›Full record

ArticleeLife2020

Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase.

Tobias Geiger, Maria Lara-Tejero, Yong Xiong, Jorge E Galán

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. From Environmental Organism to Nosocomial Threat:Antibiotics (Basel, Switzerland) · 2026
    Review
  2. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The diverse landscape of AB5-type toxins.Engineering microbiology · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Bacterial AB toxins and host-microbe interactions.Advances in microbial physiology · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tobias Geiger *Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-8528-2849
Maria Lara-Tejero *Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-1339-0859
Yong XiongDepartment of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, United States.
Jorge E GalánDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-6531-0355

Funding

Typhoid Toxin and Salmonella Typhi pathogenesisR01AI114618 · NIAID · YALE UNIVERSITY · PI GALAN, JORGE E · 2014 to 2023
$5.4M
Virulence factors of Salmonella TyphiR01AI079022 · NIAID · YALE UNIVERSITY · PI GALAN, JORGE E · 2008 to 2012
$2.0M
Virulence factors of Salmonella TyphiR56AI079022 · NIAID · YALE UNIVERSITY · PI GALAN, JORGE E · 2014 to 2014
$486k
National Institute of Allergy and Infectious Diseases AI079022NIAID NIH HHS R01 AI114618
6 · The paper itself

Abstract

Typhoid toxin is a virulence factor for the bacterial pathogen

Indexed as

Bacterial ToxinsModels, MolecularMolecular StructureMuramidaseMutationPeptidoglycanProtein TransportSalmonella typhiSubstrate SpecificityVirulence FactorsBacterial ToxinsMuramidasePeptidoglycanVirulence Factorsbacterial envelopeinfectious diseaseL-D transpeptidasemicrobiologymuramidasepeptidoglycan remodelingprotein secretionS. entericaserovar typhi

Identifiers

PMID31958059
PMCPMC6996933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.