Evidence map›Paper›PMID 31957961›Full record

ArticleStress and health : journal of the International Society for the Investigation of Stress2020

Psychological stress, cardiac symptoms, and cardiovascular risk in women with suspected ischaemia but no obstructive coronary disease.

Mayra A Gomez, Noel Bairey Merz, Jo-Ann Eastwood, Carl J Pepine, Eileen M Handberg, Vera Bittner, Puja K Mehta, David S Krantz, Viola Vaccarino, Wafia Eteiba and 1 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Stress and health : journal of the International Society for the Investigation of Stress, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
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  4. Article
  5. Review
  6. Societal, occupational, and economic considerations for women with (M)INOCA: a narrative review.International journal of occupational medicine and environmental health · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Mayra A GomezDepartment of Psychology, Palo Alto University, Palo Alto, California.
Noel Bairey MerzBarbra Streisand Women's Heart Center, Cedars-Sinai Smidt Heart Institute, Los Angeles, California.
Jo-Ann EastwoodSchool of Nursing, UCLA, Los Angeles, California.
Carl J PepineDepartment of Psychology, University of Florida, Gainesville, Florida.
Eileen M HandbergDepartment of Psychology, University of Florida, Gainesville, Florida.
Vera BittnerDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama.
Puja K MehtaDivision of Cardiology, Emory University, Atlanta, Georgia.
David S KrantzDepartment of Medical & Clinical, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Viola VaccarinoDivision of Cardiology, Emory University, Atlanta, Georgia.
Wafia EteibaDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Thomas RutledgePsychology Service, VA San Diego Healthcare System, San Diego, California.ORCID https://orcid.org/0000-0001-6048-2302
Emory University · USUniversity of Florida · USCedars-Sinai Smidt Heart Institute · USPalo Alto University · USUniformed Services University of the Health Sciences · USUniversity of Alabama at Birmingham · USUniversity of California, Los Angeles · USUniversity of California San Diego · USUniversity of Pittsburgh · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
ZONA-FREE HAMSTER OVA ASSAY AS AN INDICATOR OF MALE FERTILITYM01RR000425 · NCRR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI ANDERSON, GAIL V · 1985 to 2011
$74.2M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
CVD protection mechanisms involving ACE2/Ang-(1-7) axisR01HL056921 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 1996 to 2015
$9.2M
Brain Angiotensin In Hypertensive Neurons in CultureR37HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2003 to 2012
$5.8M
UFRCC for Cardiovascular Cell Therapy Research NetworkUM1HL087366 · NHLBI · UNIVERSITY OF FLORIDA · PI PEPINE, CARL J · 2012 to 2018
$4.7M
BRAIN ANGIOTENSIN IN HYPERTENSIVE NEURONS IN CULTURER01HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K., SUMNERS, COLIN · 1985 to 2017
$4.3M
Women's Ischemia Syndrome EvaluationU01HL064829 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KELSEY, SHERYL F. · 2001 to 2005
$3.9M
Renin Angiotensin for Coronary Microvascular DysfunctionU01HL064924 · NHLBI · UNIVERSITY OF FLORIDA · PI PEPINE, CARL J · 2001 to 2005
$2.0M
Behavioral Medicine and Cardiovascular Research TrainingT32HL069751 · NHLBI · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI KRANTZ, DAVID S. · 2003 to 2007
$1.2M
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1TR000064NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR001881NCRR NIH HHS M01 RR000425NCRR NIH HHS MO1-RR00425NHLBI NIH HHS K23 HL105787NHLBI NIH HHS K23 HL125941NHLBI NIH HHS K23 HL127262NHLBI NIH HHS N01 HV068161NHLBI NIH HHS N01 HV068162NHLBI NIH HHS N01 HV068163NHLBI NIH HHS N01 HV068164NHLBI NIH HHS N01-HV-68161NHLBI NIH HHS N01-HV-68162NHLBI NIH HHS N01-HV-68163NHLBI NIH HHS N01-HV-68164NHLBI NIH HHS R01 HL033610NHLBI NIH HHS R01 HL056921NHLBI NIH HHS R37 HL033610NHLBI NIH HHS T32 HL069751NHLBI NIH HHS U01 HL064829NHLBI NIH HHS U01 HL064914NHLBI NIH HHS U01 HL064924NHLBI NIH HHS UM1 HL087366NIA NIH HHS 1R03 AG032631NIA NIH HHS K23HL105787NIA NIH HHS K23HL125941NIA NIH HHS K23HL127262NIA NIH HHS R03 AG032631NIA NIH HHS T32 HL69751NIA NIH HHS U01 64829NIA NIH HHS U01 HL649141NIA NIH HHS U01 HL649241
6 · The paper itself

Abstract

This paper evaluated cross-sectional relationships between psychological stress and coronary artery disease (CAD) risk among women with suspected ischaemia and no obstructive coronary artery disease (INOCA). Between 1996 and 2000, 551 women with INOCA were enrolled in the Women's Ischemia Syndrome Evaluation (WISE) cohort from four U.S. institutions. Between 2009 and 2012, 376 women with INOCA were recruited from two U.S. institutions for an independent cohort study titled WISE-Coronary Vascular Dysfunction (WISE-CVD). Participants underwent coronary angiography and testing for CAD symptoms and risk factors at baseline. Psychological stress was assessed in the form of home/work stress in WISE and home/work stress and financial stress in WISE-CVD. Results showed that home/work stress predicted greater depression, functional impairment, CAD symptoms, and lower self-rated health in WISE but was inconsistent as a predictor in WISE-CVD. In contrast, >60% of WISE-CVD women reported moderate or severe financial stress. Financial stress levels predicted more CAD risk factors and cardiac symptoms, poorer self-rated health, and greater depression and functional impairment. Among women with INOCA, psychological stress was associated with CAD symptoms and CAD risk factors. The prevalence and predictive value of psychological stress in this population supports the inclusion of stress measures in future CAD research.

Indexed as

AdultAgedCohort StudiesCoronary AngiographyCoronary Artery DiseaseCross-Sectional StudiesFemaleHeart Disease Risk FactorsHemodynamicsHumansMiddle AgedMyocardial IschemiaPredictive Value of TestsRegression AnalysisStress, PsychologicalUnited Statescardiovascular diseasedepressionheart diseaseprospectivepsychological stresswomen

Identifiers

PMID31957961
PMCPMC7369220
OpenAlexW3001642909

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.