Evidence map›Paper›PMID 31957879›Full record

ArticleJournal of food science2020

Microbial composition of Kombucha determined using amplicon sequencing and shotgun metagenomics.

Muzaffer Arıkan, Alex L Mitchell, Robert D Finn, Filiz Gürel

Abstract read
In one paragraph

Article in Journal of food science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. ThaiFoods (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Kombucha as a Health-Beneficial Drink for Human Health.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Elevated abundance ofCurrent research in food science · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muzaffer ArıkanRegenerative and Restorative Medicine Research Center, Istanbul Medipol Univ., 34810, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-5162-2000
Alex L MitchellEuropean Molecular Biology Laboratory, European Bioinformatics Inst. (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-8655-7966
Robert D FinnEuropean Molecular Biology Laboratory, European Bioinformatics Inst. (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-8626-2148
Filiz GürelMolecular Biology and Genetics Dept., Faculty of Science, Istanbul Univ., 34134, Istanbul, Turkey.

Funding

Bilimsel Araştirma Projeleri Birimi, Istanbul Üniversitesi 20138Biotechnology and Biological Sciences Research Council BB/M011755/1Biotechnology and Biological Sciences Research Council BB/R015228/1European Molecular Biology LaboratoryTürkiye Bilimsel ve Teknolojik Araştirma Kurumu 215Z672
6 · The paper itself

Abstract

Kombucha, a fermented tea generated from the co-culture of yeasts and bacteria, has gained worldwide popularity in recent years due to its potential benefits to human health. As a result, many studies have attempted to characterize both its biochemical properties and microbial composition. Here, we have applied a combination of whole metagenome sequencing (WMS) and amplicon (16S rRNA and Internal Transcribed Spacer 1 [ITS1]) sequencing to investigate the microbial communities of homemade Kombucha fermentations from day 3 to day 15. We identified the dominant bacterial genus as Komagataeibacter and dominant fungal genus as Zygosaccharomyces in all samples at all time points. Furthermore, we recovered three near complete Komagataeibacter genomes and one Zygosaccharomyces bailii genome and then predicted their functional properties. Also, we determined the broad taxonomic and functional profile of plasmids found within the Kombucha microbial communities. Overall, this study provides a detailed description of the taxonomic and functional systems of the Kombucha microbial community. Based on this, we conject that the functional complementarity enables metabolic cross talks between Komagataeibacter species and Z. bailii, which helps establish the sustained a relatively low diversity ecosystem in Kombucha.

Indexed as

MicrobiotaBacteriaBeveragesFermentationFermented FoodsMetagenomeMetagenomicsSequence Analysis, DNAYeasts16Sfermented teaITSKombuchashotgun metagenomics

Identifiers

PMID31957879
PMCPMC7027524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.