ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2020
Associations Between Declining Physical and Cognitive Functions in the Lothian Birth Cohort 1936.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Multimodal Ageing Biomarkers and Plasma Proteomic Signatures Associated With All-Cause Mortality.Aging cell · 2026Article
- Article
- Physical activity, home and leisure activities, and neuropsychological performance in middle-aged and older adults living in the community.Health psychology report · 2026Article
- Adolescent IQ and performance-based measures of physical function in old age: a 54-year longitudinal study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Bidirectional association between grip strength and cognitive function in Chinese older adults: a nationwide cohort study.BMC public health · 2025Article
- A 13-Year Time-Lagged Description of General Cognitive and Functional Abilities in Older Men: A Cross-Lagged Panel Model.Journal of aging and health · 2023Article
- Sarcopenia-defining parameters, but not sarcopenia, are associated with cognitive domains in middle-aged and older European men.Journal of cachexia, sarcopenia and muscle · 2023Article
- Predictors of cognitive and physical decline: Results from the Health Aging and Body Composition Study.Frontiers in aging neuroscience · 2023Article
- Cognitive impairment and low physical function among older Mexican Americans: findings from a 20-year follow-upAnnals of epidemiology · 2022Article
- Asymmetrical Handgrip Strength Is Associated with Lower Cognitive Performance in the Elderly.Journal of clinical medicine · 2022Article
- Associations of Word Memory, Verbal Fluency, Processing Speed, and Crystallized Cognitive Ability With One-Legged Balance Performance in Mid- and Later Life.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).American journal of primatology · 2021Review
- Grip strength from midlife as an indicator of later-life brain health and cognition: evidence from a British birth cohort.BMC geriatrics · 2021Article
- Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.GeroScience · 2021Article
- Temporal emergence of age-associated changes in cognitive and physical function in vervets (Chlorocebus aethiops sabaeus).GeroScience · 2021Article
- Challenging the relationship of grip strength with cognitive status in older adults.International journal of geriatric psychiatry · 2021Article
- Article
- The bidirectional relationship between physical health and memory.Psychology and aging · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundThe ageing process is characterized by declines in physical and cognitive function. However, the relationship between these trajectories remains a topic of investigation.
methodsUsing four data waves collected triennially between ages 70 and 79, we tested for associations between multiple cognitive ability domains (verbal memory, processing speed, and visuospatial ability) and physical functions (walking speed, grip strength, and lung function). We first tested for associations between linear declines in physical and cognitive functions over the entire 9-year study period, and then, for lead-lag coupling effects between 3-year changes in cognitive and physical functions.
resultsSteeper linear decline in walking speed was moderately correlated with steeper linear declines in each cognitive domain. Steeper linear decline in grip strength was moderately correlated with steeper linear declines in verbal memory and processing speed. Lead-lag coupling models showed that decline in verbal memory was preceded by declines in walking speed and grip strength. By contrast, decline in grip strength was preceded by declines in processing speed and visuospatial ability, and decline in walking speed was preceded by decline in visuospatial ability. Following additional adjustment for covariates, only coupling effects from earlier decline in processing speed to later decline in grip strength remained significant (β = 0.545, p = .006).
conclusionOur findings provide further evidence of an association between cognitive and physical declines and point to the potential order in which these changes occur. Decline in processing speed in particular may serve as a unique early marker of declining upper body strength.
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