ArticleAge and ageing2020
Linking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study.
Article in Age and ageing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Life course shaping of allostatic load across 17 countries: Evidence from England, the U.S., Europe, China and Indonesia.medRxiv : the preprint server for health sciences · 2026Article
- Person-environment interaction processes in frailty: a scoping review.The Gerontologist · 2026Article
- Adverse Childhood Experiences and Life Course Adversity Related to Geriatric Syndromes: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Parental socioeconomic position, childhood poverty and healthy aging: retrospective and prospective study of six cohorts across 32 wealthy and developing nations.Frontiers in public health · 2026Article
- Interventions facilitating access to perinatal care for migrant women without medical insurance: a scoping review.PloS one · 2026Article
- Observational
- Mapping the Final Journey: End-Of-Life Frailty Trajectories and Cause of Death.Journal of the American Geriatrics Society · 2025Article
- Parental socioeconomic position, childhood poverty and healthy ageing: retrospective and prospective study of six cohort surveys across 32 wealthy and developing nations.medRxiv : the preprint server for health sciences · 2025Article
- Early life adversity and late life dementia in the Harmonised Cognitive Assessment Protocol network (U.S., China, England and Europe).medRxiv : the preprint server for health sciences · 2025Article
- Associations between reversible and potentially reversible cognitive frailty and falls in community-dwelling older adults in China: a longitudinal study.BMC geriatrics · 2025Article
- Association between urbanization levels and frailty among middle-aged and older adults in China: evidence from the CHARLS.BMC medicine · 2025Article
- Adult Socioeconomic Position Mediates the Association Between Childhood Socioeconomic Position and Later-Life Frailty Trajectory: A Nationally Representative Cohort Study.Innovation in aging · 2025Article
- Current status and development trends in CKD with frailty research from 2000 to 2021: a bibliometric analysis.Renal failure · 2024Review
- The relationship between childhood hunger experiences and activities of daily living disability: a mediating role of depression.BMC public health · 2024Article
- Creatinine-to-cystatin C ratio and frailty in older adults: a longitudinal cohort study.BMC geriatrics · 2024Article
- Differential interplay between multimorbidity patterns and frailty and their mutual mediation effect on mortality in old age.The journal of nutrition, health & aging · 2024Article
- Joint Association of Physical Frailty and Self-Rated Health With Mortality Among Community-Dwelling Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Article
- Dietary Sodium Restriction and Frailty among Middle-Aged and Older Adults: An 8-Year Longitudinal Study.Nutrients · 2024Article
- Association of Childhood Adversity With Frailty and the Mediating Role of Unhealthy Lifestyle: A Lifespan Analysis.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024Article
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5 authors.
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Abstract
backgroundexposures in childhood and adolescence may impact the development of diseases and symptoms in late life. However, evidence from low- and middle-income countries is scarce. In this cross-sectional study, we examined the association of early life risk factors with frailty amongst older adults using a large, nationally representative cohort of community-dwelling Chinese sample.
methodswe included 6,806 participants aged $\ge$60 years from the China Health and Retirement Longitudinal Study. We measured 13 risk factors in childhood or adolescence through self-reports, encompassing six dimensions (education, family economic status, nutritional status, domestic violence, neighbourhood and health). We used multinomial regression models to examine the association between risk factors and frailty. We further calculated the absolute risk difference for the statistically significant factors.
resultspersons with higher personal and paternal education attainment, better childhood neighbourhood quality and better childhood health status had lower risk of being frail in old age. Severe starvation in childhood was associated with higher risk of prefrailty. The risk differences of being frail were 5.6% lower for persons with a high school or above education, 1.5% lower for those whose fathers were literate, 4.8% lower for the highest neighbourhood quality and 2.9% higher for worse childhood health status compared to their counterparts.
conclusionsunfavorable socioeconomic status and worse health condition in childhood and adolescence may increase the risk of late-life frailty amongst Chinese older adults.
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