Trial reportJournal of affective disorders2020
A brief motivational intervention for enhancing medication adherence for adolescents with bipolar disorder: A pilot randomized trial.
Trial report in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Brief Motivational Intervention to Improve Medication Adherence for Adolescents With Bipolar Disorder
The Effect of Motivational Interviews on Coping, Functionality, Treatment Adherence and Quality of Life in Patients With Bipolar Disorder
Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Practical Psychosocial Management for Patients With Bipolar Disorder.American journal of psychotherapy · 2025Review
- Randomized clinical trial of a digital medication system to enhance adherence in patients with severe mental disorders.NPJ digital medicine · 2025Article
- A survey on medication adherence and influencing factors among 226 peritoneal dialysis patients in a primary hospital in China.BMC nephrology · 2025Article
- Psychological Stress Analysis to Evaluate the Effects of Transcranial Magnetic Stimulation on Mood Regulation and Quality of Life in Patients with Bipolar Disorder.Actas espanolas de psiquiatria · 2024Article
- The effect of resilience on bipolar mood during specialty clinic treatment.Journal of affective disorders · 2024Article
- Inside the Bell Jar of Social Media: A Descriptive Study Assessing YouTube Coverage of Psychotropic Medication Adherence.International journal of environmental research and public health · 2023Article
- Psychotherapy in Bipolar Depression: Effective Yet Underused.Psychiatric annals · 2023Article
- The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022Article
- Research Status in Clinical Practice Regarding Pediatric and Adolescent Bipolar Disorders.Frontiers in psychiatry · 2022Review
- Article
- Photovoice as an intervention for college students living with mental illness: A pilot study.The mental health clinician · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundYouth with bipolar disorder (BP) exhibit poor medication adherence, contributing to affective recurrence. Brief Motivational Interventions (BMIs) improve adherence among adolescents with chronic conditions.
methodsIn an open pilot series, we developed a 3-session BMI for BP adolescents targeting medication adherence and conducted a pilot randomized trial comparing Standard Care (SC) versus SC+BMI. Participants include 43 adolescents with BP prescribed psychotropic medications. We assessed medication adherence objectively via bluetooth-enabled electronic pillbox (MedTracker). A blinded evaluator assessed mood symptoms at intake, 3- and 6-months.
resultsThe BMI was well-received. Average objective medication adherence increased with time in SC+BMI, but decreased in SC-Alone (p < 0.0001). Adolescents' baseline self-rated expectation of improvement with treatment moderated the effect of treatment on improvement in adherence over time (p = 0.003). Across groups, poor adherence predicted increased likelihood of depression and hypo/mania symptoms in the subsequent two weeks; medication adherence mediated the effect of the BMI on the likelihood of depressive symptoms (p = 0.007). LIMITATIONS: Electronic pillbox use (across groups) may enhance adherence, resulting in overestimates compared with naturalistic conditions. This pilot randomized trial may have been underpowered to detect some group differences.
conclusionsA BMI offers promise as a disseminable adjunctive intervention for improving medication adherence for adolescents with BP. Future studies with larger samples can establish efficacy. NCT03203720.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.