Evidence map›Paper›PMID 31957590›Full record

ArticleThe Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics2019

Bacterial Baptism: Scientific, Medical, and Regulatory Issues Raised by Vaginal Seeding of C-Section-Born Babies.

Noel T Mueller, Suchitra K Hourigan, Diane E Hoffmann, Lauren Levy, Erik C von Rosenvinge, Betty Chou, Maria-Gloria Dominguez-Bello

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Biomolecular Mechanisms of Autoimmune Diseases and Their Relationship with the Resident Microbiota: Friend or Foe?Pathophysiology : the official journal of the International Society for Pathophysiology · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. Beneficial Effects ofFrontiers in pediatrics · 2022
    Article
  13. The emerging potential of microbiome transplantation on human health interventions.Computational and structural biotechnology journal · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Noel T MuellerNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Suchitra K HouriganNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Diane E HoffmannNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Lauren LevyNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Erik C von RosenvingeNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Betty ChouNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Maria-Gloria Dominguez-BelloNoel T. Mueller, Ph.D., M.P.H., is an Assistant Professor of Medicine, Johns Hopkins Bloomberg School of Public Health. Suchitra K. Hourigan, M.D., is a Pediatric Gastroenterology & Pediatrics, INOVA Health. Diane E. Hoffmann, J.D., Sc.M., is a Professor of Law, University of Maryland Carey School of Law. Lauren Levy, J.D., M.P.H., is Health Officer, Cecil County, MD Health Department. Erik C. von Rosenvinge, M.D., is an Associate Professor, Medicine, University of Maryland School of Medicine; Chief of Gastroenterology, VA Maryland Health Care System. Betty Chou, M.D., is an Assistant Professor of Gynecology and Obstetrics, Johns Hopkins University School of Medicine. Maria-Gloria Dominguez-Bello, Ph.D., is a Professor, Dept. of Biochemistry and Microbiology, Rutgers School of Environmental and Biological Sciences.
Johns Hopkins University · US

Funding

The Effects of Diet on the Gut Microbiome and Short Chain Fatty AcidsK01HL141589 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MUELLER, NOEL T · 2018 to 2022
$845k
NHLBI NIH HHS K01 HL141589
6 · The paper itself

Abstract

Several lines of evidence suggest that children born via Cesarean section (C-section) are at greater risk for adverse health outcomes including allergies, asthma and obesity. Vaginal seeding is a medical procedure in which infants born by C-section are swabbed immediately after birth with vaginal secretions from the mother. This procedure has been proposed as a way to transfer the mother's vaginal microbiome to the child, thereby restoring the natural exposure that occurs during vaginal birth that is interrupted in the case of babies born via C-section. Preliminary evidence indicates partial restoration of microbes. However, there is insufficient evidence to determine the health benefits of the procedure. Several studies, including trial, are currently underway. At the same time, in the clinic setting, doctors are increasingly being asked to by expectant mothers to have their babies seeded. This article reports on the current research on this procedure and the issues it raises for regulators, researchers, physicians, and patients.

Indexed as

Cesarean SectionInfant, NewbornMicrobiotaMothersBody FluidsClinical Trials as TopicFemaleHumansSkin AbsorptionUnited StatesUnited States Food and Drug AdministrationVagina

Identifiers

PMID31957590
PMCPMC7908762
OpenAlexW3002982034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.