ArticleCirculation. Heart failure2020
Long Noncoding RNA
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Article in Circulation. Heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
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Who cites it
36 citing papers in PubMed, 54 citations in OpenAlex.
- Elektra-Qki and Alien-Wt1 lncRNA-protein interaction controls myocardial ion channel expression and epicardial EMT during heart development in mice.Cellular and molecular life sciences : CMLS · 2026Article
- Separating the genetics of disease, treatment, and treatment response using graphical modeling and large-scale electronic health records.medRxiv : the preprint server for health sciences · 2026Article
- Identification and Co-expression Analysis of Differentially Expressed LncRNAs and mRNAs Regulate Intramuscular Fat Deposition in Yaks at Two Developmental Stages.Biochemical genetics · 2026Article
- Myocyte enhancer factor 2A orchestrates vascular redox homeostasis via direct transcriptional activation of SIRT1.Acta biochimica et biophysica Sinica · 2025Article
- Roles of Long Non-Coding RNAs in the Pathogenesis of Cardiovascular Disorders: Challenges and Opportunities.Journal of cardiovascular translational research · 2025Review
- Epigenetic Mechanisms in Heart Diseases.Reviews in cardiovascular medicine · 2025Review
- The role of long non-coding RNAs in cardiovascular diseases: A comprehensive review.Non-coding RNA research · 2025Review
- SUZ12-Increased NRF2 Alleviates Cardiac Ischemia/Reperfusion Injury by Regulating Apoptosis, Inflammation, and Ferroptosis.Cardiovascular toxicology · 2025Article
- Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of myocardial infarction.International journal of cardiology. Heart & vasculature · 2024Review
- Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease.Nature reviews. Cardiology · 2024Review
- Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects.Nature reviews. Cardiology · 2024Review
- Posttranscriptional Regulation by Proteins and Noncoding RNAs.Advances in experimental medicine and biology · 2024Article
- The role and medical prospects of long non-coding RNAs in cardiovascular disease.Heart failure reviews · 2023Review
- The Regulatory Effect of Receptor-Interacting Protein Kinase 3 on CaMKIIδ in TAC-Induced Myocardial Hypertrophy.International journal of molecular sciences · 2023Article
- The Role of Long Non-Coding RNAs in Cardiovascular Diseases.International journal of molecular sciences · 2023Review
- A network medicine approach to study comorbidities in heart failure with preserved ejection fraction.BMC medicine · 2023Article
- Myocyte Enhancer Factor 2A Plays a Central Role in the Regulatory Networks of Cellular Physiopathology.Aging and disease · 2023Review
- The Current Therapeutic Role of Chromatin Remodeling for the Prognosis and Treatment of Heart Failure.Biomedicines · 2023Review
- Elucidating the Influence of MPT-driven necrosis-linked LncRNAs on immunotherapy outcomes, sensitivity to chemotherapy, and mechanisms of cell death in clear cell renal carcinoma.Frontiers in oncology · 2023Article
- Overexpression of cytosolic long noncoding RNA cytb protects against pressure-overload-induced heart failure via sponging microRNA-103-3p.Molecular therapy. Nucleic acids · 2022Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 2 countries.
Junyi YuDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Yang YangDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Zaicheng XuDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Cong LanDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Caiyu ChenDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Chuanwei LiDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Zhi ChenDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Cheng YuDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Xuewei XiaDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Qiao LiaoDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Pedro A JoseDivision of Renal Disease & Hypertension, Departments of Medicine and Pharmacology/Physiology. The George Washington University School of Medicine and Health Sciences, Washington, DC (P.A.J.).
Chunyu ZengDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Gengze WuDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (J.Y., Y.Y., Z.X., C.L., C.C., C.L., Z.C., C.Y., X.X., Q.L., C.Z., G.W.).
Army Medical University · CNGeorge Washington University · US
Funding
Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GILDEA, JOHN JOSEPH · 2004 to 2020
$31.8MRENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4MRenal Dopamine Receptor & RegulationR37HL023081 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 2007 to 2016
$4.3MLipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6MNHLBI NIH HHS P01 HL074940NHLBI NIH HHS R37 HL023081NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK119652
Abstract
backgroundLong noncoding RNA (lncRNA) can regulate various physiological and pathological processes through multiple molecular mechanisms in cis and in trans. However, the role of lncRNAs in cardiac hypertrophy is yet to be fully elucidated.
methodsA mouse lncRNA microarray was used to identify differentially expressed lncRNAs in the mouse hearts following transverse aortic constriction-induced pressure overload comparing to the sham-operated samples. The direct impact of one lncRNA,
resultsA previously unannotated lncRNA, antihypertrophic interrelated transcript (
conclusions
Indexed as
AnimalsCardiomegalyDown-RegulationGene Expression RegulationHeart FailureHumansMEF2 Transcription FactorsMice, Inbred C57BLMyocytes, CardiacNeoplasm ProteinsPolycomb Repressive Complex 2Rats, Sprague-DawleyRNA, Long NoncodingTranscription FactorsMef2a protein, mouseMEF2 Transcription FactorsNeoplasm ProteinsPolycomb Repressive Complex 2RNA, Long NoncodingSUZ12 protein, humanSuz12 protein, mouseTranscription Factorscardiomegalyheart failureMEF2A, PRC2RNA, long noncoding
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