Evidence map›Paper›PMID 31957348›Full record

ArticleACR open rheumatology2020

Universal Health Literacy Precautions Are Associated With a Significant Increase in Medication Adherence in Vulnerable Rheumatology Patients.

Joel Hirsh, Patrick Wood, Angela Keniston, Dennis Boyle, Itziar Quinzanos, Liron Caplan, Lisa Davis

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in ACR open rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02694185 (Secondary Event Prevention Using Population Risk Management After PCI), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02694185 nacompletednot on this map

Secondary Event Prevention Using Population Risk Management After PCI

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2016 to 2025Enrolled5,269ConditionsMyocardial Ischemia, Rheumatic DiseasesArmsCaplan IVR
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  4. Understanding Health Equity in Patient-Reported Outcomes.The journal of allergy and clinical immunology. In practice · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Joel HirshDenver Health and Hospital Authority, University of Colorado Medical School, Denver, Aurora, Colorado.
Patrick WoodDenver Veterans Affairs and Medical Center, University of Colorado Medical School, Aurora, Colorado.
Angela KenistonDenver Health and Hospital Authority, University of Colorado Medical School, Denver, Aurora, Colorado.
Dennis BoyleDenver Health and Hospital Authority, University of Colorado Medical School, Denver, Aurora, Colorado.
Itziar QuinzanosDenver Health and Hospital Authority, University of Colorado Medical School, Denver, Aurora, Colorado.
Liron CaplanDenver Veterans Affairs and Medical Center, University of Colorado Medical School, Aurora, Colorado.
Lisa DavisDenver Health and Hospital Authority, University of Colorado Medical School, Denver, Aurora, Colorado.
Denver Health Medical Center · USDenver VA Medical Center · USUniversity of Colorado Hospital · US

Funding

UCB Biopharma SPRL
6 · The paper itself

Abstract

objectiveOur objective was to determine the impact of the Health Literacy Universal Precautions Toolkit, adapted for rheumatology, on medication adherence, patient satisfaction, and feasibility in all patients; its effect on the clinical disease activity index (CDAI) was studied in a rheumatoid arthritis (RA) subpopulation.

methodsData collected during a 6-month prospective quality assurance intervention was compared with data from a prior 6-month period. Interventions included 1) encouraging questions, 2) teach-back communication, and 3) brown-bag medication review. Analysis was performed using linear regression or generalized estimating equation (GEE) regression.

resultsDuring the intervention period, 46 physicians completed 1737 patient visits. Questions were encouraged, and teach-back communication was performed in more than 90% of visits. Brown-bag medication reviews were performed in 47% of visits overall and 69% of visits in a subgroup that received additional reminder calls. Visit duration and patient satisfaction were not significantly increased. Adherence for rheumatology-related medications that were prescribed both before and during the intervention increased by 22% (P ≤ 0.001; by GEE). Teach-back communication predicted a statistically significant improvement in medication adherence in this subpopulation (by linear regression). The mean CDAI did not improve; however, African American race and Hispanic ethnicity were associated with a decreased CDAI (by GEE).

conclusionImplementation of the Health Literacy Universal Precautions Toolkit, adapted for rheumatology, improved medication adherence in our safety-net clinic, with particularly strong effects seen with teach-back communication. In certain populations, use of the toolkit may also improve RA disease activity. This is the first study to document improved medication adherence with this intervention in a real-world setting.

Identifiers

PMID31957348
PMCPMC7011426
OpenAlexW3002713592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.