Evidence map›Paper›PMID 31957027›Full record

ArticleAlcoholism, clinical and experimental research2020

The Addictions Neuroclinical Assessment Negative Emotionality Domain Among Treatment-Seekers with Alcohol Use Disorder: Construct Validity and Measurement Invariance.

Victoria R Votaw, Matthew R Pearson, Elena Stein, Katie Witkiewitz

Abstract readValidation Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Anger and substance abuse: a systematic review and meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
    Pooled it
  3. Trial
  4. Review
  5. Observational
  6. Observational
  7. The nosology of addiction as a medical condition: a concise history and review of contemporary perspectives.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  8. Article
  9. Article
  10. Early life stress is associated with greater negative emotionality and peripheral inflammation in alcohol use disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  11. Longitudinal measurement invariance of constructs derived from the addiction cycle.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Article
  12. Observational
  13. Article
  14. Article
  15. New approaches to deep phenotyping in addictions.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Review
  16. Constructs derived from the addiction cycle predict alcohol use disorder treatment outcomes and recovery 3 years following treatment.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Victoria R VotawFrom the, Department of Psychology, (VRV, ES, KW), Center on Alcoholism, Substance Abuse, & Addictions, University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0002-4238-3383
Matthew R PearsonCenter on Alcoholism, Substance Abuse, & Addictions, (MRP), University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0003-3772-0186
Elena SteinFrom the, Department of Psychology, (VRV, ES, KW), Center on Alcoholism, Substance Abuse, & Addictions, University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0003-0404-250X
Katie WitkiewitzFrom the, Department of Psychology, (VRV, ES, KW), Center on Alcoholism, Substance Abuse, & Addictions, University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0002-1086-3067

Funding

Alcohol Research Training: Methods & MechanismsT32AA018108 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2010 to 2026
$5.6M
Precision Medicine and Recovery in a Telehealth Treatment Program for Alcohol Use DisorderR01AA022328 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2013 to 2026
$3.1M
Efficacy and neurobiological mechanisms of mobile-delivered cognitive retrainingK01AA023233 · NIAAA · UNIVERSITY OF NEW MEXICO · PI PEARSON, MATTHEW RYAN · 2014 to 2018
$832k
NIAAA NIH HHS K01 AA023233NIAAA NIH HHS R01 AA022328NIAAA NIH HHS T32 AA018108
6 · The paper itself

Abstract

backgroundThe Addictions Neuroclinical Assessment (ANA), a framework for measuring heterogeneity in alcohol use disorder (AUD), focuses on 3 domains that reflect neurobiological dysfunction in addiction and correspond to the cycles of addiction: executive function, incentive salience, and negative emotionality. Kwako and colleagues (Am J Psychiatry 176:744, 2019) validated a 3-factor model of the ANA with neuropsychological and self-report indicators among treatment-seekers and non-treatment-seekers with and without AUD. The present analysis replicated and extended these findings in a treatment-seeking sample, focusing on the negative emotionality domain.

methodsParticipants (n = 563; 58.8% male; mean age = 34.3) were part of a multisite prospective study of individuals entering AUD treatment. We examined the factor structure of the negative emotionality domain at the baseline, 6-month follow-up, and 12-month follow-up assessments. The Beck Depression Inventory, Beck Anxiety Inventory, State-Trait Anger Expression Inventory-Trait Anger Subscale, and 3 Drinker Inventory of Consequences items assessing negative affective consequences were indicators in the model.

resultsResults indicated that a 1-factor model was an excellent fit at all assessments and that the negative emotionality domain was time and gender invariant. Furthermore, negative emotionality was associated with drinking patterns and reasons for alcohol use (i.e., drinking because of negative emotions and urges/withdrawal) at all assessments.

conclusionsThis analysis provides evidence for the construct validity and measurement invariance of the ANA negative emotionality domain among AUD treatment-seekers. Future studies are needed to evaluate prospective associations between negative emotionality and specific treatment modalities, and whether individuals with greater negative emotionality are more likely to respond to treatment that targets drinking to relieve negative affective states.

Indexed as

EmotionsNegativismAdultAlcohol DrinkingAlcoholismBehavior, AddictiveExecutive FunctionFemaleHumansMaleMotivationPersonality InventoryProspective StudiesReproducibility of ResultsSurveys and QuestionnairesAddiction CycleAddictions Neuroclinical AssessmentAlcohol RelapseAlcohol Use Disorder TreatmentNegative Emotions

Identifiers

PMID31957027
PMCPMC7069798

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.