Evidence map›Paper›PMID 31956749›Full record

ReviewACS omega2020

Aggregation of Metal-Nanoparticle-Induced Fluorescence Enhancement and Its Application in Sensing.

Shuang Li, Jiangling He, Qing-Hua Xu

Abstract readReview
In one paragraph

Review in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Biogenic Cu/Ni nanotherapeutics fromOpen life sciences · 2025
    Article
  5. Article
  6. Article
  7. Highly Efficient Fluorescent Detection of Vitamin BNanomaterials (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shuang LiSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Jiangling HeNational University of Singapore (Suzhou) Research Institute, Suzhou, Jiangsu 215123, China.
Qing-Hua XuNational University of Singapore (Suzhou) Research Institute, Suzhou, Jiangsu 215123, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence-based detection methods have been widely utilized in various applications. Materials that display aggregation-induced emission (AIE) are excellent fluorescence probes to offer high contrast ratio. Chromophore-conjugated plasmonic metal nanoparticles (NPs) have been recently found to display significantly enhanced fluorescence emission upon the formation of aggregates. This new type of AIE enhancement has a totally different working mechanism. It is based on aggregation-induced plasmon coupling of metal NPs to enhance the fluorescence intensity of chromophores by increasing both the excitation efficiency and radiative decay rates, instead of reducing nonradiative decay rates as in typical AIE. AIE enhancement of chromophore-conjugated metal NPs results in a dramatic change in fluorescence intensity from severely quenched fluorescence to significantly enhanced fluorescence upon aggregate formation. It offers excellent contrast ratio and is attractive for developing platforms for highly sensitive sensing and imaging applications with reduced background. This mini-review summarizes the basic working principle and recent progress in fluorescence enhancement by coupled metal NPs on the single-molecule level, aggregation-induced plasmon coupling enhanced fluorescence of chromophore-conjugated metal NPs, and their applications in sensing. Perspectives on further utilization of this interesting phenomenon for various biomedical applications have also been discussed.

Identifiers

PMID31956749
PMCPMC6963889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.