Evidence map›Paper›PMID 31956695›Full record

ArticleInternational journal of cardiology. Heart & vasculature2020

A 90-second magnetocardiogram using a novel analysis system to assess for coronary artery stenosis in Emergency department observation unit chest pain patients.

Margarita E Pena, Claire L Pearson, Marc P Goulet, Viviane M Kazan, Alexandra L DeRita, Susan M Szpunar, Robert B Dunne

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Magnetocardiography in diagnosis of MINOCA: a case series.Frontiers in cardiovascular medicine · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Editor's response to letter.American heart journal plus : cardiology research and practice · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Observational
  15. Article
  16. Article
  17. The magnetocardiogram.Biophysics reviews · 2024
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Margarita E PenaAscension St. John Hospital, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
Claire L PearsonAscension St. John Hospital, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
Marc P GouletAscension St. John Hospital, Department of Emergency Medicine, Detroit, MI, USA.
Viviane M KazanAscension St. John Hospital, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
Alexandra L DeRitaAscension St. John Hospital, Dept. of Medical Education, Detroit, MI, USA.
Susan M SzpunarAscension St. John Hospital, Dept. of Medical Education, Detroit, MI, USA.
Robert B DunneAscension St. John Hospital, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
Wayne State University · USSt. John Hospital & Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnetocardiography (MCG) has been shown to non-invasively detect coronary artery stenosis (CAS). Emergency department (ED) patients with possible acute coronary syndrome (ACS) are commonly placed in an observation unit (OU) for further evaluation. Our objective was to compare a novel MCG analysis system with stress testing (ST) and/or coronary angiography (CA) in non-high risk EDOU chest pain patients.

methodsThis is a prospective pilot study of non-high risk EDOU chest pain patients evaluated with ST and/or CA that underwent a resting 90-second MCG scan between August 2017 and February 2018. A positive MCG scan was defined as having current dipole deviations with dispersion or splitting during the repolarization phase. ST, CA and major adverse cardiac events (MACE) 30 days and 6 months post-discharge assessed.

resultsOf 101 study patients, mean age was 56 years and 53.6% were male. MCG scan sensitivity with 95% CI was 27.3% [7.3%, 60.7%], specificity 77.8% [67.5%, 85.6%], PPV 13.0% [3.4%, 34.7%] and NPV 89.7% [80.3%, 95.2%] compared to ST, and 33.3% [7.5%, 70.7%], 78.3% [68.4%, 86.2%], 13% [5.2%, 29.0%] and 92.3% [88.2%, 95.1%] respectively compared to ST and CA. No patients had positive ST, CA or MACE 30 days and 6 months post-discharge.

conclusionThis pilot study suggests a resting 90-second MCG scan shows promise in evaluating EDOU chest pain patients for CAS and warrants further study as an alternative testing modality to identify patients safe for discharge. Larger studies are needed to assess accuracy of MCG using this novel analysis system.

Indexed as

Chest painCoronary stenosisEmergency departmentMagnetocardiographyObservation unit

Identifiers

PMID31956695
PMCPMC6956743
OpenAlexW2999327828

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.