Evidence map›Paper›PMID 31956556›Full record

ArticleJournal of traditional and complementary medicine2020

Microarray analysis of genes from animals treated with a traditional formulation

Pratheppa Rajagopal, David Raj Chellappan, Sriram Sridharan, Brindha Pemiah, Sridharan Krishnaswamy, Swaminathan Sethuraman, KalpoondiRajan Sekar, Uma Maheswari Krishnan

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Therapeutic efficacy ofJournal of traditional and complementary medicine · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pratheppa RajagopalCentre for Nanotechnology & Advanced Biomaterials, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
David Raj ChellappanCentre for Advanced Research in Indian Systems of Medicine, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
Sriram SridharanCentre for Advanced Research in Indian Systems of Medicine, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
Brindha PemiahCentre for Advanced Research in Indian Systems of Medicine, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
Sridharan KrishnaswamySchool of Chemical & Biotechnology, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
Swaminathan SethuramanCentre for Nanotechnology & Advanced Biomaterials, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
KalpoondiRajan SekarCentre for Nanotechnology & Advanced Biomaterials, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
Uma Maheswari KrishnanCentre for Nanotechnology & Advanced Biomaterials, SASTRA Deemed-to-be University, Thanjavur, 613 401, Tamil Nadu, India.
SASTRA University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional medicinal preparations have not received global acceptance, and their therapeutic benefits remain disputed due to lack of scientific evidence on their mechanism of action. Microarray analysis has emerged as a powerful technique that can aid in understanding the complex signaling networks activated by these formulations and thereby assess their beneficial as well as adverse effects.

aimThe present work aims to investigate the differential influence of MATERIALS AND

methodsThe RNA from the liver of rats treated with different doses of

resultsThe results revealed several molecular targets that could contribute to the therapeutic effects of

conclusionThus the microarray data for the CPV treated animals has revealed molecular targets that may be responsible for the various known therapeutic effects and also identified new beneficial effects of CPV.

Indexed as

AyurvedaChandraprabhaVatiMicroarray analysis

Identifiers

PMID31956556
PMCPMC6957807
OpenAlexW2964590464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.