Evidence map›Paper›PMID 31956545›Full record

ArticleQuantitative imaging in medicine and surgery2020

An unsupervised semi-automated pulmonary nodule segmentation method based on enhanced region growing.

He Ren, Lingxiao Zhou, Gang Liu, Xueqing Peng, Weiya Shi, Huilin Xu, Fei Shan, Lei Liu

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

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  10. Radiomics: a primer on high-throughput image phenotyping.Abdominal radiology (New York) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

He RenShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Lingxiao ZhouShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Gang LiuShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Xueqing PengShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Weiya ShiShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Huilin XuShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Fei ShanShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Lei LiuShanghai Public Health Clinical Center & Institutes of Biomedical Sciences, School of Basic Medical Sciences, School of Data Science, Fudan University, Shanghai 200032, China.
Shanghai Public Health Clinical Center · CNShanghai University of Medicine and Health Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNowadays, computer technology is getting popular for clinical aided diagnosis, especially in the direction of medical images. It makes physician diagnosis of lung nodules more efficient by providing them with reliable and accurate segmentation.

methodsA region growing based semi-automated pulmonary nodule segmentation algorithm (ReGANS) was developed with three improvements: an automatic threshold calculation method, a lesion area pre-projection method, and an optimized region growing method. The algorithm can quickly and accurately segment a whole lung nodule in a set of computed tomography (CT) images based on an initial manual point.

resultsThe average time taken for ReGANS to segment 1 pulmonary nodule was 0.83s, and the probability rand index (PRI), global consistency error (GCE), and variation of information (VoI) from a comparison between the algorithm and the radiologist's 2 manual results were 0.93, 0.06, and 0.3 for the boundary range (BR), and 0.86, 0.06, 0.3 for the precise range (PR). The number of images covered by one pulmonary nodule in a CT image set was also evaluated to compare the segmentation algorithm with the radiologist's results, with an error rate of 15%. At the same time, the results were verified in multiple data sets to validate the robustness.

conclusionsCompared with other algorithms, ReGANS can segment the lung nodule image region more quickly and more precisely. The experimental results show that ReGANS can assist medical imaging diagnosis and has good clinical application value. It also provides a faster and more convenient method for pre-data preparation of intelligent algorithms.

Indexed as

computed tomography (CT)Lung cancerpulmonary nodulesegmentation

Identifiers

PMID31956545
PMCPMC6960427
OpenAlexW2996030281

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.