Evidence map›Paper›PMID 31956535›Full record

ArticleQuantitative imaging in medicine and surgery2020

Vascular branching geometry relating to portal hypertension: a study of liver microvasculature in cirrhotic rats by X-ray phase-contrast computed tomography.

Mengyu Sun, Wenjuan Lv, Xinyan Zhao, Lili Qin, Yuqing Zhao, Xiaohong Xin, Jianbo Jian, Xiaodong Chen, Chunhong Hu

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mengyu SunSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China.
Wenjuan LvSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China.
Xinyan ZhaoLiver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Lili QinSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China.
Yuqing ZhaoSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China.
Xiaohong XinSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China.
Jianbo JianRadiation Oncology Department, Tianjin Medical University General Hospital, Tianjin 300070, China.
Xiaodong ChenKey Laboratory of Optoelectronic Information Technology, Ministry of Education (Tianjin University), Tianjin 300072, China.
Chunhong HuSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China.
Tianjin Medical University · CNBeijing Friendship Hospital · CNTianjin Medical University General Hospital · CNTianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortal hypertension is one of the major complications of cirrhosis. The changes in hepatic microvasculature are considered as critical pathophysiological characteristics of portal hypertension. X-ray phase-contrast computed tomography (PCCT) is a new imaging technique that can detect liver vessels at a micrometric level without contrast agents.

methodsIn this study, male Sprague-Dawley rats with liver cirrhosis induced by carbon tetrachloride (CCl

resultsThe results demonstrated that the branch angle and MD significantly increased in the CCl

conclusionsThe branch angle and MD could accurately distinguish portal pressure in cirrhotic rats, suggesting that branching geometric characteristics of the microvasculature may be a promising marker in the prognosis of portal hypertension in liver cirrhosis.

Indexed as

branch angleMurray’s deviation (MD)Portal hypertensionthree-dimensional visualization (3D visualization)X-ray phase-contrast computed tomography (X-ray PCCT)

Identifiers

PMID31956535
PMCPMC6960415
OpenAlexW2990578224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.