Evidence map›Paper›PMID 31956525›Full record

ArticleQuantitative imaging in medicine and surgery2020

Assessment of left ventricular myocardial work in Turner syndrome patients: insights from the novel non-invasive pressure-strain loop analysis method.

Felix Sebastian Oberhoffer, Hashim Abdul-Khaliq, Anna-Maria Jung, Michael Zemlin, Tilman R Rohrer, Mohamed Abd El Rahman

Open access · diamondAbstract read
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Article in Quantitative imaging in medicine and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

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  13. Non-invasive left ventricular myocardial work indices in healthy adolescents at rest.The international journal of cardiovascular imaging · 2021
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4 · The record

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5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Felix Sebastian OberhofferDepartment of Pediatric Cardiology, Saarland University Hospital, Homburg (Saar), Germany.
Hashim Abdul-KhaliqDepartment of Pediatric Cardiology, Saarland University Hospital, Homburg (Saar), Germany.
Anna-Maria JungDepartment of Pediatric Endocrinology, Saarland University Hospital, Homburg (Saar), Germany.
Michael ZemlinDepartment of Pediatric Endocrinology, Saarland University Hospital, Homburg (Saar), Germany.
Tilman R RohrerDepartment of Pediatric Endocrinology, Saarland University Hospital, Homburg (Saar), Germany.
Mohamed Abd El RahmanDepartment of Pediatric Cardiology, Saarland University Hospital, Homburg (Saar), Germany.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTurner syndrome (TS), a relatively rare chromosomal disease, is associated with multiple cardiovascular risk factors that possibly lead to increased left ventricular afterload and functional impairment. The aim of this study was to investigate whether alterations in myocardial work and work efficiency can be found in TS patients through left ventricular pressure-strain loop analysis (PSL).

methodsThirty-eight patients with TS and 19 healthy, age-matched controls were recruited for this study. Global peak systolic strain (GLPS) and PSL of the left ventricle was assessed in study participants. TS patients whose history included coarctation of the aorta or prior cardiac surgery were excluded from GLPS and PSL analyses (n=5).

resultsMedian age was 16.00 years in the TS group and 16.35 years in the control group (P=0.236). GLPS did not show significant differences between both groups (P=0.524). TS patients demonstrated, compared to controls, a significantly higher global myocardial work index (BSA) (mean ± SD: 1,497±505

conclusionsTS patients showed signs of increased myocardial workload that were only detectable through the novel PSL analysis method and not through GLPS. Moreover, elevated resting heart rate was linked with increased myocardial workload in TS patients. Further studies will have to investigate whether TS patients may develop advanced left ventricular systolic dysfunction later in life.

Indexed as

Echocardiographymyocardial workpressure-strain loop (PSL)Turner syndrome (TS)

Identifiers

PMID31956525
PMCPMC6960421
OpenAlexW2988171686

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.