Evidence map›Paper›PMID 31956411›Full record

ArticleJournal of animal science and biotechnology2020

Early inoculation with caecal fermentation broth alters small intestine morphology, gene expression of tight junction proteins in the ileum, and the caecal metabolomic profiling of broilers.

Yujie Gong, Wenrui Xia, Xueting Wen, Wentao Lyu, Yingping Xiao, Hua Yang, Xiaoting Zou

Open access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  7. Nutrients · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yujie Gong1State Key Laboratory for Quality and Safety of Agro-products, Institute of Quality and Standards for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021 China.
Wenrui Xia1State Key Laboratory for Quality and Safety of Agro-products, Institute of Quality and Standards for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021 China.
Xueting Wen2Key Laboratory for Molecular Animal Nutrition of Ministry of Education, Feed Sciences Institute, College of Animal Sciences, Zhejiang University (Zijingang Campus), Hangzhou, 310058 China.
Wentao Lyu2Key Laboratory for Molecular Animal Nutrition of Ministry of Education, Feed Sciences Institute, College of Animal Sciences, Zhejiang University (Zijingang Campus), Hangzhou, 310058 China.
Yingping Xiao2Key Laboratory for Molecular Animal Nutrition of Ministry of Education, Feed Sciences Institute, College of Animal Sciences, Zhejiang University (Zijingang Campus), Hangzhou, 310058 China.ORCID 0000-0002-7949-1126
Hua Yang2Key Laboratory for Molecular Animal Nutrition of Ministry of Education, Feed Sciences Institute, College of Animal Sciences, Zhejiang University (Zijingang Campus), Hangzhou, 310058 China.
Xiaoting Zou1State Key Laboratory for Quality and Safety of Agro-products, Institute of Quality and Standards for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021 China.
Ministry of Agriculture · LVZheJiang Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe establishment of stable microbiota in early life is beneficial to the individual. Changes in the intestinal environment during early life play a crucial role in modulating the gut microbiota. Therefore, early intervention to change the intestinal environment can be regarded as a new regulation strategy for the growth and health of poultry. However, the effects of intestinal environmental changes on host physiology and metabolism are rarely reported. This study was conducted to investigate the effects of early inoculation with caecal fermentation broth on small intestine morphology, gene expression of tight junction proteins in the ileum, and cecum microbial metabolism of broilers.

resultsOur data showed that early inoculation with caecal fermentation broth could improve intestine morphology. The small intestine villus height was significantly increased (

conclusionsThese results provide insight into intestinal metabolomics and confirm that early inoculation with caecal fermentation broth can be used as a potential strategy to improve intestinal health of broilers.

Indexed as

BroilersEarly inoculationGene expressionIntestine morphologyMetabolomics profiling

Identifiers

PMID31956411
PMCPMC6961334
OpenAlexW3013222668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.