Evidence map›Paper›PMID 31956404›Full record

ArticleAntimicrobial resistance and infection control2020

Epidemiological characteristics of carbapenem-resistant

Hui Zhou, Kui Zhang, Wei Chen, Junhao Chen, Jie Zheng, Chang Liu, Li Cheng, Wanqing Zhou, Han Shen, Xiaoli Cao

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
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  14. Antimicrobial agents and chemotherapy · 2023
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  17. The Antibacterial Activity ofMolecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hui Zhou *1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Kui Zhang *1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Wei Chen2Clinical Research Center, the second hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, 210003 China.
Junhao Chen1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Jie Zheng1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Chang Liu1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Li Cheng1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Wanqing Zhou1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Han Shen1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.
Xiaoli Cao1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Gulou District, Nanjing, Jiangsu People's Republic of China.ORCID 0000-0001-5928-6304
Nanjing Drum Tower Hospital · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In total, 97 carbapenem-resistant Methods: Antimicrobial susceptibility was determined; followed by determination of the prevalence of resistance determinants, including extended-spectrum β-lactamase (ESBLs), plasmid-mediated AmpC enzyme (pAmpCs), plasmid-mediated quinolone resistance genes (PMQRs), fosfomycin resistance gene and exogenously acquired 16S rRNA methyltransferase (16S-RMTase) using PCR and DNA sequencing. The sequence types (STs) of CRE were determined by multi-locus sequence typing (MLST). The plasmid profiles were detected by PCR-based replicon typing (PBRT). Results: All the CRE strains displayed high MIC Conclusions: The treatment for infections caused by CRE isolates is challenged by the presence of multiple resistance determinants and plasmid replicons. Our results highlighted the expansion of

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBacterial Typing TechniquesCarbapenem-Resistant EnterobacteriaceaeChinaDrug Resistance, Multiple, BacterialHospitalsHumansKlebsiella InfectionsMicrobial Sensitivity TestsMultilocus Sequence TypingPhylogenyPlasmidsSequence Analysis, DNAAnti-Bacterial AgentsBacterial ProteinsCarbapenemaseCREKlebsiella pneumoniaePlasmid repliconSequence type

Identifiers

PMID31956404
PMCPMC6958626
OpenAlexW3005172699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.