Evidence map›Paper›PMID 31956305›Full record

ArticleFrontiers in aging neuroscience2019

Peripheral Maintenance of the Axis SIRT1-SIRT3 at Youth Level May Contribute to Brain Resilience in Middle-Aged Amateur Rugby Players.

Rubén Corpas, Elisabeth Solana, Adrian De la Rosa, Sara Sarroca, Christian Griñán-Ferré, Mireia Oriol, Emili Corbella, Eduard Rodríguez-Farré, Jose Vina, Mercè Pallàs and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Rubén CorpasInstitut d'Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Centre Network for Epidemiology and Public Health (CIBERESP), Barcelona, Spain.
Elisabeth SolanaDepartament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, IDIBAPS, Barcelona, Spain.
Adrian De la RosaFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.
Sara SarrocaInstitut d'Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Centre Network for Epidemiology and Public Health (CIBERESP), Barcelona, Spain.
Christian Griñán-FerréUnitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia i Ciències de l'Alimentació, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain.
Mireia OriolClinic Institute of Nephrology and Urology (ICNU), Hospital Clínic, Barcelona, Spain.
Emili CorbellaUnitat de Risc Vascular Medicina Interna, Hospital Universitari de Bellvitge, IDIBELL, CIBER Fisiopatología Obesidad y Nutrición (CIBEROBN), Barcelona, Spain.
Eduard Rodríguez-FarréInstitut d'Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Centre Network for Epidemiology and Public Health (CIBERESP), Barcelona, Spain.
Jose VinaFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.
Mercè PallàsUnitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia i Ciències de l'Alimentació, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain.
David Bartrés-FazDepartament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, IDIBAPS, Barcelona, Spain.
Mari Carmen Gomez-CabreraFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.
Coral SanfeliuInstitut d'Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Centre Network for Epidemiology and Public Health (CIBERESP), Barcelona, Spain.
Universitat de Barcelona · ESUniversitat de València · ESConsejo Superior de Investigaciones Científicas · ESBellvitge University Hospital · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESHospital Clínic de Barcelona · ESInstitut d'Investigacions Biomèdiques de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical exercise performed regularly is known to improve health and to reduce the risk of age-related diseases. Furthermore, there is some evidence of cognitive improvement in physically active middle-aged and older adults. We hypothesized that long-term physically active middle-aged men may have developed brain resilience that can be detected with the analysis of peripheral blood markers. We aimed to analyze the activation of pathways potentially modulated by physical activity in a cohort of healthy amateur rugby players (

Indexed as

brain resiliencemiddle-aged and young menphysical exerciseSIRT1SIRT3whole-blood gene expression

Identifiers

PMID31956305
PMCPMC6951402
OpenAlexW2995026874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.