ReviewFrontiers in behavioral neuroscience2019
The Sexual Motivation of Male Rats as a Tool in Animal Models of Human Health Disorders.
Review in Frontiers in behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
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- Differential genetic background control state-dependent courtship ultrasonic vocalizations in mice.Neurogenetics · 2025Article
- Evaluation and research progress on rodent models of late-onset hypogonadism: a comprehensive review.The Canadian journal of urology · 2025Review
- Prophylactic role of omega 3 fatty acids in bisphenol F-induced sexual and erectile dysfunction is associated with penile redox homeostasis.Biochemistry and biophysics reports · 2025Article
- Nesfatin-1 Neurons in the Ventral Premammillary Nucleus Integrate Metabolic and Reproductive Signals in Male Rats.International journal of molecular sciences · 2025Article
- Stress, hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-gonadal axis, and aggression.Metabolic brain disease · 2024Review
- Editorial: Sexual behavior research: towards an understanding of CNS and spinal cord modulation of male sexual behavior and sexual dysfunctions.Frontiers in neuroscience · 2024Article
- Neurophysiology of male sexual arousal-Behavioral perspective.Frontiers in behavioral neuroscience · 2023Review
- Crosstalk between the endocannabinoid and mid-brain dopaminergic systems: Implication in dopamine dysregulation.Frontiers in behavioral neuroscience · 2023Review
- A new approach to 'on-demand' treatment of lifelong premature ejaculation by treatment with a combination of a 5-HTFrontiers in neuroscience · 2023Article
- The elusive concept of sexual motivation: can it be anchored in the nervous system?Frontiers in neuroscience · 2023Review
- Photocatalytic Degradation of Some Typical Antibiotics: Recent Advances and Future Outlooks.International journal of molecular sciences · 2022Review
- A Protocol for the Non-invasive Method of Ultrasound Separation During the Sociosexual Vocal-Non-contact Model in Rats.Frontiers in behavioral neuroscience · 2022Article
- Anticipatory 50-kHz Precontact Ultrasonic Vocalizations and Sexual Motivation: Characteristic Pattern of Ultrasound Subtypes in an Individual Analyzed Profile.Frontiers in behavioral neuroscience · 2021Article
- Glutamate in Male and Female Sexual Behavior: Receptors, Transporters, and Steroid Independence.Frontiers in behavioral neuroscience · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Normal or dysfunctional sexual behavior seems to be an important indicator of health or disease. Many health disorders in male patients affect sexual activity by directly causing erectile dysfunction, affecting sexual motivation, or both. Clinical evidence indicates that many diseases strongly disrupt sexual motivation and sexual performance in patients with depression, addiction, diabetes mellitus and other metabolic disturbances with obesity and diet-related factors, kidney and liver failure, circadian rhythm disorders, sleep disturbances including obstructive sleep apnea syndrome, developmental and hormonal disorders, brain damages, cardiovascular diseases, and peripheral neuropathies. Preclinical studies of these conditions often require appropriate experimental paradigms, including animal models. Male sexual behavior and motivation have been intensively investigated over the last 80 years in animal rat model. Sexual motivation can be examined using such parameters as: anticipatory behavior and 50-kHz ultrasonic vocalizations reflecting the emotional state of rats, initiation of copulation, efficiency of copulation, or techniques of classical (pavlovian) and instrumental conditioning. In this review article, we analyze the behavioral parameters that describe the sexual motivation and sexual performance of male rats in the context of animal experimental models of human health disorders. Based on analysis of the parameters describing the heterogeneous and complex structure of sexual behavior in laboratory rodents, we propose an approach that is useful for delineating distinct mechanisms affecting sexual motivation and sexual performance in selected disease states and the efficacy of therapy in preclinical investigations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.