Evidence map›Paper›PMID 31956285›Full record

ArticleReproductive medicine and biology2020

Tubulointerstitial nephritis antigen-like 1 deficiency alleviates age-dependent depressed ovulation associated with ovarian collagen deposition in mice.

Masato Akaiwa, Emiko Fukui, Hiromichi Matsumoto

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Low TINAGL1 expression is a marker for poor prognosis in breast cancer.Journal of cancer research and clinical oncology · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Masato AkaiwaLaboratory of Animal Breeding and Reproduction Division of Animal Science School of Agriculture Utsunomiya University Utsunomiya Japan.
Emiko FukuiLaboratory of Animal Breeding and Reproduction Division of Animal Science School of Agriculture Utsunomiya University Utsunomiya Japan.
Hiromichi MatsumotoLaboratory of Animal Breeding and Reproduction Division of Animal Science School of Agriculture Utsunomiya University Utsunomiya Japan.ORCID https://orcid.org/0000-0002-0104-6866
Utsunomiya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to examine whether the Tinagl1 might be associated with ovulation in aged females and reproductive age-associated fibrosis in the stroma of the ovary.

methodsTo address the ovulatory ability and quality of ovulated oocytes, we induced ovulation by treatment with equine chorionic gonadotropin (eCG) and human chorionic gonadotropin (hCG) followed by in vitro fertilization. We also performed Picrosirius Red (PSR) staining to evaluate ovarian collagen deposition.

resultsAs compared to ovulation in 8- to 9-month-old

conclusionsThe alleviation of age-associated depression of ovulation was caused by delayed ovarian collagen deposition in

Indexed as

agingmatricellular proteinmouseovulationTinagl1

Identifiers

PMID31956285
PMCPMC6955583
OpenAlexW2973826507

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.