ArticleNeuron2020
Estimation of Current and Future Physiological States in Insular Cortex.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
117 citing papers in PubMed, 1 synthesis or guideline pooled it, 223 citations in OpenAlex.
- "Wanting" versus "needing" related value: An fMRI meta-analysis.Brain and behavior · 2022Pooled it
- The Impact of Alpha-Neurofeedback Training on Gastric Slow Wave Activity and Heart Rate Variability in Humans.Neurogastroenterology and motility · 2025Trial
- Article
- Comparative insights into insula structure and function.Nature neuroscience · 2026Review
- An atlas of primate insular cortex reveals a signal-processing strategy in von Economo neurons.Nature cell biology · 2026Article
- Uncovering internal states with a robust shared-state multi-neuron GLM-HMM framework.bioRxiv : the preprint server for biology · 2026Article
- Signaling of salience and prediction errors by anterior insula neurons.Biochemical and biophysical research communications · 2026Article
- Article
- Excitatory paraventricular thalamus-posterior insular cortex circuit mediates pain-anxiety comorbidity in diabetic neuropathy.Translational psychiatry · 2026Article
- Altered amygdala and striatal responsivity and prediction error encoding of temporal reward dynamics in post-trauma psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Machine learning-based identification of abnormal functional connectivity in obesity across different metabolic states.Communications medicine · 2026Article
- Sensory and palatability coding of taste stimuli in cortex involves dynamic and asymmetric cortico-amygdalar interactions.Journal of neurophysiology · 2026Article
- The encoding of interoceptive-based predictions by the paraventricular nucleus of the thalamus D2R+ neurons.iScience · 2026Article
- Activation of Insula-Accumbal Projection Neurons Is Required for Relapse-Like Behaviour Following Opioid Self-Administration.Addiction biology · 2026Article
- Neural coding in gustatory cortex reflects consumption decisions: evidence from conditioned taste aversion.Frontiers in systems neuroscience · 2026Article
- Insular cortex predictions regulate glucose homeostasis.bioRxiv : the preprint server for biology · 2025Article
- Interpreting Anxiety Disorders From the Perspective of Interoceptive Computational Models.Brain and behavior · 2025Review
- Divergent prefrontal cortex circuits regulate cued food seeking under distinct metabolic or emotional states.Nature communications · 2025Article
- Linear and categorical coding units in the mouse gustatory cortex drive population dynamics and behavior in taste decision-making.bioRxiv : the preprint server for biology · 2025Article
- The interoceptive origin of reinforcement learning.Trends in cognitive sciences · 2025Review
57 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Interoception, the sense of internal bodily signals, is essential for physiological homeostasis, cognition, and emotions. While human insular cortex (InsCtx) is implicated in interoception, the cellular and circuit mechanisms remain unclear. We imaged mouse InsCtx neurons during two physiological deficiency states: hunger and thirst. InsCtx ongoing activity patterns reliably tracked the gradual return to homeostasis but not changes in behavior. Accordingly, while artificial induction of hunger or thirst in sated mice via activation of specific hypothalamic neurons (AgRP or SFO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.