Evidence map›Paper›PMID 31955639›Full record

ArticleJournal of the American Heart Association2020

Medication Errors and Blood Pressure Control Among Patients Managed for Hypertension in Public Ambulatory Care Clinics in Botswana.

Pooja Gala, Veronica Moshokgo, Bhavna Seth, Kegomoditswe Ramasuana, Emmanuel Kazadi, Rudy M'buse, Solomon Pharithi, Kabelo Gobotsamang, Paige Szymanowski, Ruth Olyn Kerobale and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Disparities in Prevalence and Barriers to Hypertension Control: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Nurses and emergency nursing care in Botswana.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. May Measurement Month 2019: an analysis of blood pressure screening results from Botswana.European heart journal supplements : journal of the European Society of Cardiology · 2021
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Pooja GalaSection of Hospital Medicine Department of General Medicine University of Chicago IL.
Veronica MoshokgoDepartment of Public Health Imperial College London United Kingdom.
Bhavna SethDepartment of Medicine Beth Israel Deaconess Hospital Boston MA.
Kegomoditswe RamasuanaDepartment of Medicine Scottish Livingstone Hospital Molepolole Botswana.
Emmanuel KazadiDepartment of Medicine Scottish Livingstone Hospital Molepolole Botswana.
Rudy M'buseDepartment of Medicine Scottish Livingstone Hospital Molepolole Botswana.
Solomon PharithiDepartment of Medicine Kweneng East District Management Team Molepolole Botswana.
Kabelo GobotsamangDepartment of Medicine Thamaga Hospital Thamaga Botswana.
Paige SzymanowskiDepartment of Medicine Beth Israel Deaconess Hospital Boston MA.
Ruth Olyn KerobaleDepartment of Medicine Kweneng East District Management Team Molepolole Botswana.
Kelennetse BalekileDepartment of Medicine Scottish Livingstone Hospital Molepolole Botswana.
Jacques TshimbalangaDepartment of Medicine Kweneng East District Management Team Molepolole Botswana.
Jane Tieng'oDepartment of Medicine Scottish Livingstone Hospital Molepolole Botswana.
Neo TapelaBotswana Harvard AIDS Institute Partnership Gaborone Botswana.
Tomer BarakDepartment of Medicine Beth Israel Deaconess Hospital Boston MA.
Beth Israel Deaconess Hospital · USBotswana Harvard AIDS Institute Partnership · BWImperial College London · GBLivingstone Hospital · ZAUniversity of Oxford · GB

Funding

J. NRSA Training CoreTL1TR002388 · NCATS · UNIVERSITY OF CHICAGO · PI ALI KESHAVARZIAN, Sonia Kupfer · 2017 to 2026
$6.7M
NCATS NIH HHS TL1 TR002388
6 · The paper itself

Abstract

Background The prevalence of hypertension in low- and middle-income countries is rapidly increasing, with most cases undiagnosed and many poorly controlled among those diagnosed. Medication reconciliation studies from high-income countries have demonstrated a high occurrence of antihypertensive medication errors and a strong association between medication errors and inadequate blood pressure control, but data from low- and middle-income countries are lacking. Methods and Results We conducted a cross-sectional study from April to October 2018 of adult patients on pharmacologic management for known hypertension at 7 public health facilities in Kweneng East District, Botswana. Our aims included to evaluate the frequency of uncontrolled hypertension, the frequency and type of medication errors causing discrepancies between patient-reported and prescribed antihypertensive medications, and the association between medication errors and uncontrolled hypertension. Descriptive analyses and multivariable logistic regression were used. The prevalence of uncontrolled hypertension was 55% among 280 enrolled adult patients, and 95 (34%) had ≥1 medication error. The most common errors included patients taking medications incorrectly (11.1%; 31/280), patients omitting medications (7.9%; 22/280), and unfilled prescriptions caused by pharmacy stock outs (7.5%%; 21/280). Uncontrolled hypertension was significantly associated with having ≥1 medication error compared with no errors (adjusted odds ratio, 3.26; 95% CI, 1.75-6.06;

Indexed as

Ambulatory Care FacilitiesMedication AdherenceMedication ErrorsMedication ReconciliationPractice Patterns, Physicians'AdultAgedAntihypertensive AgentsBlood PressureBotswanaCross-Sectional StudiesDrug PrescriptionsDrug UtilizationFemaleHumansHypertensionAntihypertensive Agentshypertensionlow‐ and middle‐income countriesmedication errorsmedication reconciliation

Identifiers

PMID31955639
PMCPMC7033820
OpenAlexW2999465708

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.