Evidence map›Paper›PMID 31955621›Full record

ReviewInnate immunity2020

Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives.

Vladimir Y Toshchakov, Artur Javmen

Open access · goldAbstract readReview
In one paragraph

Review in Innate immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.Journal of enzyme inhibition and medicinal chemistry · 2024
    Article
  8. Article
  9. Review
  10. TLR5-Derived, TIR-Interacting Decoy Peptides to Inhibit TLR Signaling.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Article
  11. Article
  12. Article
  13. The Role of Toll-Like Receptors 2 and 4 in the Pathogenesis of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vladimir Y ToshchakovDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-7942-2294
Artur JavmenDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · US

Funding

Deciphering the architecture of TLR signaling complexesR01AI082299 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI TOSHCHAKOV, VLADIMIR Y. · 2010 to 2020
$3.8M
NIAID NIH HHS R01 AI082299
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Membrane PermeabilityDrug DiscoveryHumansImmunity, InnateImmunomodulationPeptidesProtein BindingProtein DomainsSignal TransductionToll-Like ReceptorsPeptidesToll-Like Receptorscell-permeable decoy peptidesprotein interaction inhibitorsTIR domainsTLR signalingTLR signalosome

Identifiers

PMID31955621
PMCPMC6974878
OpenAlexW3001517470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.