ArticleKorean journal of family medicine2021
Malnutrition, Its Attributes, and Impact on Quality of Life: An Epidemiological Study among β-Thalassemia Major Children.
Article in Korean journal of family medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Article
- Clinical, Hematological, and Nutritional Profiling of Thalassemia Patients: Insights From a Cross-Sectional Study.Anemia · 2026Article
- Dietary Patterns Among Patients With Beta-Thalassemia Major in Vietnam.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Factors Affecting the Quality of Life of Children With Transfusion-Dependent Thalassemia: A Cross-Sectional Study.Acta medica academica · 2025Article
- The growth and development of children with β-thalassemia major one year after allogeneic hematopoietic stem cell transplantation.Translational pediatrics · 2024Article
- Quality of life and thalassemia in India: A scoping review.Journal of family medicine and primary care · 2024Article
- Health-related quality of life with standard and curative therapies in thalassemia: A narrative literature review.Annals of the New York Academy of Sciences · 2024Review
- Association of age to nutritional status and muscle mass in children with transfusion-dependentFrontiers in nutrition · 2024Article
- Nutritional studies in patients with β-thalassemia major: A short review.Acta bio-medica : Atenei Parmensis · 2023Review
- Detection of endocrine disorders in young children with multi-transfused thalassemia major.Italian journal of pediatrics · 2021Article
- Quality of Life and Related Paraclinical Factors in Iranian Patients with Transfusion-Dependent Thalassemia.Journal of environmental and public health · 2021Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndia is home to a large number of thalassemic children. Despite malnutrition being an essential determinant of their therapeutic goals and quality of life (QoL), it was hardly ever explored. With this background, this study aimed to estimate the proportion of β-thalassemia major (β-TM) children experiencing malnutrition, its attributes, and impact on their QoL.
methodsThis cross-sectional, hospital-based, analytical observational study was conducted among 328 β-TM children attending the thalassemia day care unit of a medical college from May 2016 to April 2017, with a structured schedule. Data were analyzed following appropriate statistical methods using SPSS statistical package ver. 16.0 (SPSS Inc., Chicago, IL, USA).
resultsAmong the study participants, 48.2% were malnourished with a mean body mass index of 13.9 kg/m2 . In the multivariable logistic regression model, participants' age (adjusted odds ratio [AOR], 1.15; 95% confidence interval [CI], 1.02-1.29), caste (AOR, 2.11; 95% CI, 1.23-3.60), mothers' educational level (AOR, 2.05; 95% CI, 1.22- 3.44), blood transfusion frequency (AOR, 1.25; 95% CI, 1.16-1.31), and palpable spleen size (AOR, 1.22; 95% CI, 1.08-1.37) were significant predictors of malnutrition after adjusting for pre-transfusion hemoglobin level and hemolytic facies status. In multiple linear regression analysis, malnutrition negatively impacted total QoL (unstandardized beta [standard error], -4.4 [1.7]; P=0.009) and various domains of the study participants except the social and school domains adjusted for age, sex, caste, place of residence, parents' educational level, and socioeconomic status.
conclusionAlmost half of the study participants had malnutrition. Malnutrition had a negative impact on their QoL.
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