ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Effects of exercise and diet in patients with incurable gastroesophageal cancer: the RADICES study.JNCI cancer spectrum · 2026Trial
- Equipercentile Equating of Scores From Common Patient-Reported Outcome Measures of Role, Social, and Emotional Functioning in Patients With Cancer.Psycho-oncology · 2026Article
- Psychometric evaluation of separate anxiety and depression item banks - potential supplements to the EORTC CAT Core.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Who uses self-management apps from the OncoAppstore: description of characteristics, symptoms, and functioning of a real-world user population.Journal of cancer survivorship : research and practice · 2026Article
- The Long-Term Quality of Life Study for Patients Received Chest Wall Reconstruction by Using 3D-Printed PEEK Implants.Thoracic cancer · 2026Article
- Evaluating the use of prior information to individualise start item selection for the EORTC CAT core.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Cutaneous melanoma.Nature reviews. Disease primers · 2025Review
- Using prior information to individualize start item selection when assessing physical functioning with the EORTC CAT Core.Health and quality of life outcomes · 2025Article
- Comparing the contents of patient-reported outcome measures for fatigue: EORTC CAT Core, EORTC QLQ-C30, EORTC QLQ-FA12, FACIT, PRO-CTCAE, PROMIS, Brief Fatigue Inventory, Multidimensional Fatigue Inventory, and Piper Fatigue Scale.Health and quality of life outcomes · 2024Article
- Development of standard computerised adaptive test (CAT) settings for the EORTC CAT Core.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Monitoring aerobic capacity in cancer survivors using self-reported questionnaires: criterion validity and responsiveness.Journal of patient-reported outcomes · 2023Article
- Development of a diverse set of standard short forms based on the EORTC CAT Core item banks.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Applying multidimensional computerized adaptive testing to the MSQOL-54: a simulation study.Health and quality of life outcomes · 2023Article
- Patient-reported outcome measures for physical function in cancer patients: content comparison of the EORTC CAT Core, EORTC QLQ-C30, SF-36, FACT-G, and PROMIS measures using the International Classification of Functioning, Disability and Health.BMC medical research methodology · 2023Article
- Linking the European Organisation for Research and Treatment of Cancer Item Library to the Common Terminology Criteria for Adverse Events.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022Article
- Investigating the response scale of the EORTC QLQ-C30 in German cancer patients and a population survey.Health and quality of life outcomes · 2021Article
- Brazilian Validation of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group (QLG) Computerised Adaptive Tests (CAT) Core.Current oncology (Toronto, Ont.) · 2021Article
- Health-Related Quality of Life Assessment in Patients with Myelodysplastic Syndromes: Evidence from Randomized Clinical Trials.Clinical practice and epidemiology in mental health : CP & EMH · 2021Review
- Assessment Practice of Patient-Centered Outcomes in Surgical Neuro-Oncology: Survey-Based Recommendations for Clinical Routine.Frontiers in oncology · 2021Article
- Quality of Life in Patients with Gynecological Cancers: A Web-Based Study.Asian Pacific journal of cancer prevention : APJCP · 2020Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundThe European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group (QLG) has developed computerised adaptive tests (CATs) for the 14 functional and symptom domains of the EORTC QLQ-C30 quality of life questionnaire. This is expected to optimise measurement precision, relevance to patients and flexibility. Here, we present the first international validation of the EORTC CAT Core.
methodsA heterogeneous sample of 699 cancer patients scheduled for chemotherapy and/or radiotherapy was recruited across seven European countries. The EORTC CAT Core and all QLQ-C30 items were administered to participants before and after initiating treatment. Correlations between CAT and QLQ-C30 scores and floor/ceiling effects were calculated. Using several grouping variables, relative validity (cross-sectional known groups difference), responsiveness (changes over time) and relative sample size requirements of the CAT compared to the QLQ-C30 were estimated.
resultsCorrelations of the CAT and QLQ-C30 ranged from 0.81 to 0.93 across domains. The mean relative reduction in floor and ceiling effects using the CAT was 42% (range 3-99%). Analyses of known groups validity and responsiveness indicated that, across domains, mean sample size requirements for the CAT were 72% and 70%, respectively, of those using the QLQ-C30.
conclusionsThe EORTC CAT Core measures the same domains as the QLQ-C30 with reduced floor/ceiling effects. The CAT generally facilitated the use of smaller samples (about 30% smaller on average) without loss of power compared to the QLQ-C30. Based on this study, the EORTC QLG will release the EORTC CAT Core for general use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.