Evidence map›Paper›PMID 31955254›Full record

ReviewCurrent cardiology reports2020

Obstructive Sleep Apnea, Hypertension, and Cardiovascular Risk: Epidemiology, Pathophysiology, and Management.

Liann Abu Salman, Rachel Shulman, Jordana B Cohen

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06782737 (Effect of the Mediterranean Type Diet Versus Standard Diet on Cardiometabolic Indicator in Patients With Obstructive Sleep Apnea), which is not on this map. Cited by 174 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06782737 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Effect of the Mediterranean Type Diet Versus Standard Diet on Cardiometabolic Indicator in Patients With Obstructive Sleep Apnea

TypeinterventionalSponsorCoordinación de Investigación en Salud, MexicoRan2024 to 2026Enrolled120ConditionsObstructive Sleep ApneaArmsDietetic interventión with mediterranean diet
3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Racial and Ethnic Disparities in the Diagnosis and Treatment of Obstructive Sleep Apnea: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
  2. Systematic review of changes in extracellular vesicles associated with obstructive sleep apnoea: implications for diagnosis and treatment.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. A Systematic Review of Publications on the Associations Between Sleep Architecture and Arterial Hypertension.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Pooled it
  7. Pooled it
  8. Effects of Exercise on Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  9. Soluble P-selectin levels in patients with obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liann Abu SalmanDepartment of Internal Medicine, Lankenau Medical Center, Wynnewood, PA, USA.
Rachel ShulmanDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jordana B CohenRenal-Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. jco@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewGiven the rising prevalence of obstructive sleep apnea (OSA), we aimed to review the epidemiologic and pathophysiologic relationship of OSA, hypertension, and cardiovascular disease, and to summarize recent advances in the treatment of OSA. RECENT

findingsOSA is associated with an elevated risk of hypertension and cardiovascular disease. Several pathophysiologic factors contribute to the relationship between OSA and vascular risk, including neurohormonal dysregulation, endothelial dysfunction, and inflammation. While CPAP reduces blood pressure, it has not been demonstrated to reduce cardiovascular risk. The combination of CPAP and weight loss has a synergistic effect on blood pressure and several metabolic parameters. Adherence to CPAP is poor across studies, potentially contributing to the attenuation of perceived cardiovascular benefit from CPAP therapy. A greater emphasis on adherence to CPAP and the combination of CPAP and weight loss are central to reducing cardiovascular risk among individuals with OSA.

Indexed as

Continuous Positive Airway PressureBlood PressureCardiovascular DiseasesHumansHypertensionObesityRisk FactorsSleep Apnea, ObstructiveBlood pressureCardiovascular diseaseContinuous positive airway pressureHypertensionObesityObstructive sleep apnea

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.