Evidence map›Paper›PMID 31955235›Full record

ArticleNeuroradiology2020

Abnormal degree centrality in delayed encephalopathy after carbon monoxide poisoning: a resting-state fMRI study.

Kaifu Wu, Meng Liu, Laichang He, Yongming Tan

Open access · hybridAbstract read
In one paragraph

Article in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kaifu WuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Meng LiuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Laichang HeDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Yongming TanDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. tanyongming1209@163.com.ORCID http://orcid.org/0000-0002-5771-1036
Nanchang University · CN

Funding

National Natural Science Foundation of China 81460329Natural Science Foundation of Jiangxi Province 20192ACBL20039、20181BAB205063
6 · The paper itself

Abstract

purposeTo explore neuropathologic mechanisms in functional brain regions in patients with delayed encephalopathy after carbon monoxide poisoning (DEACMP) from the perspective of the brain network nodes by resting-state functional magnetic resonance imaging (rs-fMRI).

methodsThe fMRI and cognitive assessments were performed in 25 patients with DEACMP and 25 age-, sex- and education-matched healthy controls (HCs). Data analysis was performed via the degree centrality (DC) method. Then, the associations between the cognitive assessments and DC in the identified abnormal brain regions were assessed by using a correlation analysis.

resultsCompared with the HCs, the DEACMP patients displayed significantly decreased DC values in the right superior frontal gyrus, right precentral gyrus, right angular gyrus, right marginal gyrus, right hippocampus, and left thalamus but increased DC values in the right inferior frontal gyrus, right cingulate gyrus, left superior temporal gyrus, left medial temporal gyrus, right lingual gyrus, and right posterior cerebellar lobe, pons, and midbrain (GRF correction, voxel P value < 0.001, cluster P value < 0.01). The correlation analysis in the DEACMP group revealed that there was a negative correlation between the DC values in the right hippocampus and MMSE scores, whereas a positive correlation was observed in the right cingulate gyrus.

conclusionsPatients with DEACMP exhibited abnormal degree centrality in the brain network. This finding may provide a new approach for examining the neuropathologic mechanisms underlying DEACMP.

Indexed as

Magnetic Resonance ImagingAdultBrain DiseasesBrain MappingCarbon Monoxide PoisoningCase-Control StudiesCognitive DysfunctionFemaleHumansImage Interpretation, Computer-AssistedMaleBrainDegree centralityDelayed encephalopathy after carbon monoxide poisoningFunctional magnetic resonance imagingResting-state

Identifiers

PMID31955235
PMCPMC7186243
OpenAlexW2999440604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.