SynthesisInternational journal of colorectal disease2020
Prevalence and risk factors for postoperative delirium in patients with colorectal carcinoma: a systematic review and meta-analysis.
Synthesis in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Perioperative neurocognitive disorder in colorectal cancer surgery: a systematic review of incidence, mechanisms, and interventions.Frontiers in surgery · 2025Pooled it
- Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery: An Individual Patient Data Meta-Analysis.JAMA network open · 2023Pooled it
- Risk Factors for Postoperative Delirium in Patients Undergoing Major Head and Neck Cancer Surgery: A Meta-analysis.Cancer nursingPooled it
- Overtime work of anesthesiologists is associated with increased delirium in older patients admitted to intensive care unit after noncardiac surgery: a secondary analysis.BMC anesthesiology · 2024Trial
- Cognitive Impact of Colorectal Cancer Surgery in Elderly Patients: A Narrative Review.Cancers · 2026Review
- Relevance and Feasibility of a "Geriatric Delirium Pass" for Older Patients with Elective Surgeries: Findings from a Multi-Methods Study.Geriatrics (Basel, Switzerland) · 2026Article
- Development and Validation of a Postoperative Delirium Prediction Model for Patients Undergoing Gastrointestinal Surgery.Clinical and experimental gastroenterology · 2026Article
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- Preoperative Prognostic Nutritional Index Is a Predictive Factor for Postoperative Delirium in Elderly Patients with Femoral Neck Fracture.Clinical interventions in aging · 2025Article
- Delirium risk and mortality in people with pre-existing severe mental illness: a retrospective cohort study using linked datasets in England.Psychological medicine · 2024Article
- Correlation of preoperative inflammatory factors and emotional disorders with postoperative delirium in patients with craniocerebral trauma.World journal of psychiatry · 2024Article
- CRP/albumin, Glasgow prognostic score, and prognostic nutritional index as a predictor of mortality among delirium patients.Irish journal of medical science · 2024Article
- Strategies to prevent postoperative delirium: a comprehensive evaluation of anesthesia selection and drug intervention.Frontiers in psychiatry · 2024Review
- Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study.Acta psychiatrica Scandinavica · 2023Article
- Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study.Frontiers in neuroscience · 2023Article
- Transcutaneous Electrical Acupoint Stimulation for Preventing Postoperative Delirium: A Meta-Analysis.Neuropsychiatric disease and treatment · 2023Review
- Perioperative neurocognitive disorders: A narrative review focusing on diagnosis, prevention, and treatment.CNS neuroscience & therapeutics · 2022Review
- Preoperative Low Physical Activity is a Predictor of Postoperative Delirium in Patients with Gastrointestinal Cancer: A Retrospective Study.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- The assessment of risk factors for postoperative delirium using cubic spline curves in gastroenterological surgery.Surgery today · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePostoperative delirium (POD) is a common, but severe complication in elderly patients undergoing surgery for colorectal cancer, but the prevalence and potential risk factors for POD were not well established. Therefore, a meta-analysis was preformed to clarify the prevalence and risk factors of POD in patients undergoing surgery for colorectal cancer.
methodsPubMed, Embase, and the Cochrane Library were systematically searched on August 2019. Studies were included if they reported the prevalence and risk factors of POD in patients undergoing colorectal cancer surgery. The guidelines for critically appraising studies of prevalence or incidence of a health problem were used to assess the quality of included studies. Pooled odds ratios (ORs) for individual risk factors were estimated using the Mantel-Haenszel methods in random effect model. Sensitive analyses based on different inclusion criteria were conducted to explore whether the current meta-analysis was enough credible and robust.
resultsSeventeen studies totaling 4472 patients undergoing colorectal cancer surgery were included. The pooled prevalence of POD is 14% (95% CI = 12-17%). Twelve significant risk factors were identified in pooled analysis including older age (OR = 1.10), sex (OR = 1.87), history of psychiatric disease (OR = 6.47), comorbidities (OR = 2.17), prognostic nutritional index (OR = 1.12), physical status (OR = 1.27), American Society of Anesthesiologists Score (ASA Scores) (OR = 1.65), history of alcohol abuse (OR = 2.23), postoperative pain management (OR = 1.91), perioperative blood transfusion (OR = 2.37), cognitive status (OR = 1.91), and lower serum level of albumin (OR = 0.58).
conclusionsPOD is a frequent complication in patients undergoing surgery with colorectal cancer. Several risk factors including history of psychiatric disease, transfusion, comorbidities, male gender, and old age were significant predictors for POD.
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