Evidence map›Paper›PMID 31954763›Full record

ArticleThe Journal of hospital infection2020

Sources of viral respiratory infections in Canadian acute care hospital healthcare personnel.

S Buckrell, B L Coleman, S A McNeil, K Katz, M P Muller, A Simor, M Loeb, J Powis, S P Kuster, J M Di Bella and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of hospital infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

S BuckrellDalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
B L ColemanDalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Sinai Health System, Toronto, ON, Canada. Electronic address: b.coleman@utoronto.ca.
S A McNeilCanadian Center for Vaccinology, Dalhousie University, IWK Health Centre, and Nova Scotia Health Authority, Halifax, NS, Canada.
K KatzNorth York General Hospital and Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
M P MullerDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Unity Health, Toronto, ON, Canada.
A SimorDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
M LoebDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
J PowisToronto East Health Network, Department of Medicine, University of Toronto, Toronto, ON, Canada.
S P KusterDivision of Infectious Diseases and Hospital Epidemiology, University Hospital and University of Zurich, Zürich, Switzerland.
J M Di BellaSinai Health System, Toronto, ON, Canada.
K K L ColemanSinai Health System, Toronto, ON, Canada; Parkwood Institute, London Health Sciences Centre, London, ON, Canada.
S J DrewsCanadian Blood Services, Edmonton, AB, Canada; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
P KohlerDivision of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital, St. Gallen, Switzerland.
A McGeerSinai Health System, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Canadian Healthcare Worker Study Group
University of Toronto · CASinai Health System · CAUniversity Hospital of Zurich · CHCanadian Blood Services · CAUniversity of Alberta · CADalhousie University · CAHealth Sciences Centre · CAMcMaster University · CAPublic Health Ontario · CAUniversity of St. Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundViral respiratory illnesses are common causes of outbreaks and can be fatal to some patients.

aimTo investigate the association between laboratory-confirmed viral respiratory infections and potential sources of exposure during the previous 7 days.

methodsIn this nested case-control analysis, healthcare personnel from nine Canadian hospitals who developed acute respiratory illnesses during the winters of 2010/11-2013/14 submitted swabs that were tested for viral pathogens. Associated illness diaries and the weekly diaries of non-ill participants provided information on contact with people displaying symptoms of acute respiratory illness in the previous week. Conditional logistic regression assessed the association between cases, who were matched by study week and site with controls with no respiratory symptoms.

findingsThere were 814 laboratory-confirmed viral respiratory illnesses. The adjusted odds ratio (aOR) of a viral illness was higher for healthcare personnel reporting exposures to ill household members [7.0, 95% confidence interval (CI) 5.4-9.1], co-workers (3.4, 95% CI 2.4-4.7) or other social contacts (5.1, 95% CI 3.6-7.1). Exposures to patients with respiratory illness were not associated with infection (aOR 0.9, 95% CI 0.7-1.2); however, healthcare personnel with direct patient contact did have higher odds (aOR 1.3, 95% CI 1.1-1.6). The aORs for exposure and for direct patient contact were similar for illnesses caused by influenza.

conclusionCommunity and co-worker contacts are important sources of viral respiratory illness in healthcare personnel, while exposure to patients with recognized respiratory infections is not associated. The comparatively low risk associated with direct patient contact may reflect transmission related to asymptomatic patients or unrecognized infections.

Indexed as

AdultAgedCanadaCase-Control StudiesCross InfectionFemaleHealth PersonnelHospitalsHumansInfluenza, HumanMaleMiddle AgedRespiratory Tract InfectionsRisk FactorsSurveys and QuestionnairesVirus DiseasesAdultExposureHealthcare workerHospitalRespiratoryTransmissionViral

Identifiers

PMID31954763
PMCPMC7172118
OpenAlexW2999579219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.