Evidence map›Paper›PMID 31954339›Full record

ArticlePregnancy hypertension2020

Identifying hypertension in pregnancy using electronic medical records: The importance of blood pressure values.

Lu Chen, Susan M Shortreed, Thomas Easterling, T Craig Cheetham, Kristi Reynolds, Lyndsay A Avalos, Aruna Kamineni, Victoria Holt, Romain Neugebauer, Mary Akosile and 5 more

Open access · greenAbstract read
In one paragraph

Article in Pregnancy hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Lu ChenKaiser Permanente Washington Health Research Institute, Seattle, WA, United States. Electronic address: lu.chen@kp.org.
Susan M ShortreedKaiser Permanente Washington Health Research Institute, Seattle, WA, United States; University of Washington, Seattle, WA, United States.
Thomas EasterlingUniversity of Washington, Seattle, WA, United States.
T Craig CheethamKaiser Permanente Southern California, Department of Research & Evaluation, Pasadena, CA, United States; Chapman University, School of Pharmacy, Irvine, CA, United States.
Kristi ReynoldsKaiser Permanente Southern California, Department of Research & Evaluation, Pasadena, CA, United States.
Lyndsay A AvalosKaiser Permanente Northern California, Division of Research, Oakland, CA, United States.
Aruna KamineniKaiser Permanente Washington Health Research Institute, Seattle, WA, United States.
Victoria HoltUniversity of Washington, Seattle, WA, United States.
Romain NeugebauerKaiser Permanente Northern California, Division of Research, Oakland, CA, United States.
Mary AkosileKaiser Permanente Washington Health Research Institute, Seattle, WA, United States.
Nerissa NanceKaiser Permanente Northern California, Division of Research, Oakland, CA, United States.
Zoe Bider-CanfieldKaiser Permanente Southern California, Department of Research & Evaluation, Pasadena, CA, United States.
Rod L WalkerKaiser Permanente Washington Health Research Institute, Seattle, WA, United States.
Sylvia E BadonKaiser Permanente Northern California, Division of Research, Oakland, CA, United States.
Sascha DublinKaiser Permanente Washington Health Research Institute, Seattle, WA, United States; University of Washington, Seattle, WA, United States.
Kaiser Permanente · USKaiser Permanente Washington Health Research Institute · USUniversity of Washington · US

Funding

Moderate Hypertension in Pregnancy: Safety and Effectiveness of TreatmentR01HD082141 · NICHD · KAISER FOUNDATION RESEARCH INSTITUTE · PI DUBLIN, SASCHA · 2015 to 2018
$3.8M
NICHD NIH HHS R01 HD082141
6 · The paper itself

Abstract

objectiveTo incorporate blood pressure (BP), diagnoses codes, and medication fills from electronic medical records (EMR) to identify pregnant women with hypertension. STUDY

designA retrospective cohort study of singleton pregnancies at three US integrated health delivery systems during 2005-2014.

main outcome measuresWomen were considered hypertensive if they had any of the following: (1) ≥2 high BPs (≥140/90 mmHg) within 30 days during pregnancy (High BP); (2) an antihypertensive medication fill in the 120 days before pregnancy and a hypertension diagnosis from 1 year prior to pregnancy through 20 weeks gestation (Treated Chronic Hypertension); or (3) a high BP, a hypertension diagnosis, and a prescription fill within 7 days during pregnancy (Rapid Treatment). We described characteristics of these pregnancies and conducted medical record review to understand hypertension presence and severity.

resultsOf 566,624 pregnancies, 27,049 (4.8%) met our hypertension case definition: 24,140 (89.2%) with High BP, 5,409 (20.0%) with Treated Chronic Hypertension, and 5,363 (19.8%) with Rapid Treatment (not mutually exclusive). Of hypertensive pregnancies, 19,298 (71.3%) received a diagnosis, 9,762 (36.1%) received treatment and 11,226 (41.5%) had a BP ≥ 160/110. In a random sample (n = 55) of the 7,559 pregnancies meeting the High BP criterion with no hypertension diagnosis, clinical statements about hypertension were found in medical records for 58% of them.

conclusionIncorporating EMR BP identified many pregnant women with hypertension who would have been missed by using diagnosis codes alone. Future studies should seek to incorporate BP to study treatment and outcomes of hypertension in pregnancy.

Indexed as

AdultAntihypertensive AgentsCohort StudiesDelivery of Health Care, IntegratedDrug PrescriptionsElectronic Health RecordsFemaleHumansHypertensionHypertension, Pregnancy-InducedPregnancyPregnancy Complications, CardiovascularRetrospective StudiesUnited StatesAntihypertensive Agents

Identifiers

PMID31954339
PMCPMC7096129
OpenAlexW2997005173

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.