Evidence map›Paper›PMID 31953974›Full record

ArticleJournal of veterinary internal medicine2020

Efficacy of dexamethasone, salbutamol, and reduced respirable particulate concentration on aerobic capacity in horses with smoke-induced mild asthma.

Stephanie L Bond, Persephone Greco-Otto, Jacqueline MacLeod, Angelica Galezowski, Warwick Bayly, Renaud Léguillette

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Airway remodeling in horses with mild and moderate asthma.Journal of veterinary internal medicine · 2022
    Article
  5. Glucocorticoid treatment in horses with asthma: A narrative review.Journal of veterinary internal medicine · 2021
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Stephanie L BondFaculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-6700-5127
Persephone Greco-OttoFaculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Jacqueline MacLeodFaculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Angelica GalezowskiFaculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Warwick BaylyDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington.ORCID https://orcid.org/0000-0002-1403-6245
Renaud LéguilletteFaculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-0381-3640
University of Calgary · CAWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMild asthma in horses decreases racing performance and impairs gas exchange. The efficacy of treatment on performance is unknown. HYPOTHESIS: Treatment targeting lung inflammation improves ANIMALS: Thoroughbred polo horses (n = 12) with smoke-induced mild asthma. Horses were exposed to increased ambient particulate matter (35.51 μg/m

methodsProspective, randomized, placebo-controlled, double-blinded clinical trial. All horses completed 3

resultsHorses' mucus scores improved significantly from day -8 to 20 by 1.27 ± .38 (P = .01). There was a significant increase in CONCLUSIONS AND CLINICAL IMPORTANCE: This study highlighted the key role of improved air quality on functionally important airway inflammation. Evidence provided is central to increasing owner compliance regarding improved air quality for the treatment and prevention of mild asthma.

Indexed as

SmokeAlbuterolAnimalsAsthmaBronchodilator AgentsDexamethasoneDouble-Blind MethodFemaleHorse DiseasesHorsesMaleParticulate MatterPhysical Conditioning, AnimalProspective StudiesRespirationTreatment OutcomeAlbuterolBronchodilator AgentsDexamethasoneParticulate MatterSmokeaerobic energyanaerobic energydustsmoke-induced airway cytology

Identifiers

PMID31953974
PMCPMC7096652
OpenAlexW2999375498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.