Evidence map›Paper›PMID 31953902›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2020

Kaposi sarcoma among people living with HIV in the French DAT'AIDS cohort between 2010 and 2015.

I Poizot-Martin, V Obry-Roguet, C Duvivier, C Lions, T Huleux, C Jacomet, T Ferry, A Cheret, C Allavena, F Bani-Sadr and 11 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Kaposi Sarcoma in People Living with HIV: Is it Water under the Bridge?Mediterranean journal of hematology and infectious diseases · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 13 institutions in 2 countries.

I Poizot-MartinAix-Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, APHM Sainte-Marguerite, Service d'Immuno-Hématologie Clinique, Marseille, France.ORCID https://orcid.org/0000-0002-5676-5411
V Obry-RoguetAix-Marseille Université, APHM Sainte-Marguerite, Service d'Immuno-Hématologie Clinique, Marseille, France.
C DuvivierService de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, APHP-Hôpital Necker-Enfants Malades, Paris, France.
C LionsAix-Marseille Université, APHM Sainte-Marguerite, Service d'Immuno-Hématologie Clinique, Marseille, France.
T HuleuxService Universitaire des Maladies Infectieuses et du Voyageur - Centre Hospitalier G. DRON, Tourcoing, France.
C JacometCentre Hospitalier Universitaire de Clermont-Ferrand, Département des Maladies Infectieuses et Tropicales, Clermont Ferrand, France.
T FerryService de Maladies Infectieuses, Hospices Civils de Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France.
A CheretSorbonne Paris Cité, EA7327, Université Paris Descartes, Paris, France.
C AllavenaService des Maladies Infectieuses et Tropicales, CHU Hôtel-Dieu, Nantes, France.
F Bani-SadrDépartement de Médecine Interne, Maladies Infectieuses et Immunologie Clinique, Hêpital Robert Debré, Centre Hospitalier Universitaire, Reims, France.
R PalichService des Maladies Infectieuses et Tropicales, GHPS Pitié Salpêtrière APHP, Paris, France.
A CabiéService des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Martinique, Fort-de-France, France.
A FresardCentre Hospitalier Universitaire de Saint-Étienne, Département des Maladies Infectieuses et Tropicales, Saint-Etienne, France.
P PuglieseCHU de Nice, Universite Côte d'Azur, Nice, France.
P DelobelCHU de Toulouse, Service des Maladies Infectieuses et Tropicales-INSERM, UMR1043-Université Toulouse III Paul Sabatier, Toulouse, France.
I LamauryDépartement d'Infectiologie, Dermatologie et Immunologie Clinique, Pointe-à-Pitre Cedex, France.
L Hustache-MathieuService des Maladies Infectieuses et Tropicales, CHRU de Besançon - Hôpital Jean Minjoz, Besançon, France.
S BrégigeonAix-Marseille Université, APHM Sainte-Marguerite, Service d'Immuno-Hématologie Clinique, Marseille, France.
A MakinsonCentre Hospitalier Universitaire de Montpellier, Département des Maladies Infectieuses et Tropicales, INSERM U1175/IRD UMI 233, Montpellier, France.
D ReyLe Trait d'Union, Centre de Soins de l'infection par le VIH, Hôpitaux Universitaires, Strasbourg, France.
Dat'AIDS study group
Inserm · FRAix-Marseille Université · FRCentre Hospitalier de Tourcoing · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Universitaire de Reims · FRCentre Hospitalier Universitaire de Saint-Étienne · FRDélégation Paris 5 · FRHôpital Necker-Enfants Malades · FRHôpitaux Universitaires de Strasbourg · FRUniversité Claude Bernard Lyon 1 · FRUniversité Côte d'Azur · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough antiretroviral therapy (ART) has reduced the risk of Kaposi sarcoma (KS), KS cases still occur in HIV-infected people.

objectiveTo describe all KS cases observed between 2010 and 2015 in a country with high ART coverage.

methodsRetrospective study using longitudinal data from 44 642 patients in the French Dat'AIDS multicenter cohort. Patients' characteristics were described at KS diagnosis according to ART exposure and to HIV-plasma viral load (HIV-pVL) (≤50 or >50) copies/mL.

resultsAmong the 209 KS cases diagnosed during the study period, 33.2% occurred in ART naïve patients, 17.3% in ART-experienced patients and 49.5% in patients on ART, of whom 23% for more than 6 months. Among these patients, 24 (11.5%) had HIV-pVL ≤50 cp/mL, and 16 (66%) were treated with a boosted-PI-based regimen. The distribution of KS localization did not differ by ART status nor by year of diagnosis. LIMITATIONS: Data on human herpesvirus 8, treatment modalities for KS and response rate were not collected.

conclusionHalf of KS cases observed in the study period occurred in patients not on ART, reflecting the persistence of late HIV diagnosis. Factors associated with KS in patients on ART with HIV-pVL ≤50 cp/mL remain to be explored.

Indexed as

Acquired Immunodeficiency SyndromeHerpesvirus 8, HumanHIV InfectionsSarcoma, KaposiHumansRetrospective Studies

Identifiers

PMID31953902
PMCPMC7318618
OpenAlexW3000070502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.