Evidence map›Paper›PMID 31953859›Full record

SynthesisEpilepsia2020

Epilepsy-specific patient-reported outcome measures of children's health-related quality of life: A systematic review of measurement properties.

Holly Crudgington, Morwenna Rogers, Hannah Morris, Paul Gringras, Deb K Pal, Christopher Morris

Open access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Epilepsia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Holly CrudgingtonBasic and Clinical Neuroscience Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0003-1048-4953
Morwenna RogersUniversity of Exeter Medical School, University of Exeter, Exeter, UK.ORCID 0000-0002-6039-238X
Hannah MorrisUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Paul GringrasEvelina London Children's Hospital, London, UK.
Deb K PalBasic and Clinical Neuroscience Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0003-2655-0564
Christopher MorrisUniversity of Exeter Medical School, University of Exeter, Exeter, UK.ORCID 0000-0002-9916-507X
University of Exeter · GBKing's College London · GBLondon Women's Clinic · GB

Funding

Charles Sykes Epilepsy Research TrustCharles Sykes Epilepsy Research Trust (DKP)CIHR 201503MOP-342469Department of Health RP-PG-0615-20007European Union Programme of the Seventh Framework 602531Medical Research Council MR/N026063/1NIHR Specialist Biomedical Research Centre for Mental Health of South London and Maudsley NHS Foundation TrustWaterloo Foundation 164-3020
6 · The paper itself

Abstract

objectiveTo identify and appraise published evidence of the measurement properties for epilepsy-specific patient-reported outcome measures (PROMs) of children's health-related quality of life (HRQoL).

methodsWe searched multiple databases for studies evaluating the measurement properties of English-language epilepsy-specific PROMs of children's HRQoL. We assessed the methodological quality using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidance. We extracted data about the content validity, construct validity, internal consistency, test-retest reliability, proxy reliability, responsiveness, and precision, and assessed the measurement properties with reference to standardized criteria.

resultsWe identified 27 papers that evaluated 11 PROMs. Methodological quality was variable. Construct validity, test-retest reliability, and internal consistency were more commonly assessed. Quality of Life in Childhood Epilepsy (QoLCE) questionnaires are parent-reported and evaluated more than other PROMs; QoLCE-55 has good and replicated evidence for structural and construct validity and internal consistency. Health-Related Quality of Life Measure for Children with Epilepsy (CHEQoL) has both child and parent-reported versions and good evidence of content, structural, and construct validity. SIGNIFICANCE: This review identified two leading candidate epilepsy-specific PROMs for measuring health-related quality of life in children. Establishing evidence of the responsiveness of PROMs is a priority to help the interpretation of meaningful change scores.

Indexed as

Patient Reported Outcome MeasuresAdolescentChildChild HealthChild, PreschoolEpilepsyHumansInfantNeuropsychological TestsQuality of LifeReproducibility of ResultsTreatment Outcomechildrenepilepsypaediatricpatient-reported outcome measuresyoung people

Identifiers

PMID31953859
PMCPMC7065094
OpenAlexW2998921892

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.