ArticleSurgical endoscopy2020
Lesion size and circumferential range identified as independent risk factors for esophageal stricture after endoscopic submucosal dissection.
Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Risk Prediction Models of Esophageal Strictures After Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2025Pooled it
- Efficacy of endoscopic submucosal tunnel dissection versus endoscopic submucosal dissection for superficial esophageal neoplastic lesions: a systematic review and meta-analysis.Surgical endoscopy · 2021Pooled it
- Prospective multicenter validation of a clinical score model for muscular injury risk stratification during esophageal endoscopic submucosal dissection.Surgical endoscopy · 2026Article
- Adjunctive Stenting After Esophageal ESD: Dissecting the Data Delivers Doubt.Digestive diseases and sciences · 2026Article
- Association of DPP4 with esophageal stricture progression and the Hippo-YAP pathway.Animal models and experimental medicine · 2026Article
- ENDOCUT Q coagulation fraction is associated with esophageal stricture after endoscopic submucosal dissection.Surgical endoscopy · 2026Article
- Steroid with Temporary Stent Versus Steroid Alone for Preventing Stricture After Endoscopic Submucosal Dissection for Early Esophageal Cancer.Digestive diseases and sciences · 2026Article
- An Integrated Circumferential Proportion and Defect Length Index for Predicting Esophageal Stricture After ESD in Large Mucosal Defects ≥6 cm.Journal of clinical medicine · 2026Article
- Risk Factors and Prophylaxis for Post-Procedural Stricture After Esophageal Endoscopic Submucosal Dissection.The Korean journal of helicobacter and upper gastrointestinal research · 2026Article
- Correlation between sarcopenia and esophageal stenosis following endoscopic submucosal dissection and construction of a postoperative stenosis risk model.World journal of gastroenterology · 2026Article
- A multicenter retrospective study on the risk factors of stricture formation after moderate circumferential defect resection in esophageal endoscopic submucosal dissection.Surgical endoscopy · 2026Observational
- Risk factors for esophageal stricture after circumferential endoscopic submucosal dissection: a preliminary, multicenter, retrospective, case-control study.Frontiers in medicine · 2026Article
- Risk factors of fever following endoscopic radiofrequency ablation for early esophageal squamous cell carcinoma and precancerous lesions.World journal of gastrointestinal surgery · 2025Article
- Predictors of post-endoscopic submucosal dissection stricture in superficial esophageal cancer patients receiving oral steroid prophylaxis.Scientific reports · 2025Article
- Endoscopic Image-Based Prediction of Esophageal Stenosis after ESD Using Mucosal Defect Metrics.Annals of surgical oncology · 2025Article
- Risk stratification for stricture formation after endoscopic submucosal dissection for esophageal dysplasia.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025Article
- Feasibility and predictors of same-day discharge following endoscopic submucosal dissection for early esophageal cancer.BMC gastroenterology · 2025Article
- Steroid lifting method during endoscopic submucosal dissection: A novel strategy for stricture prevention.DEN open · 2025Article
- Comparative study on different endoscopic submucosal dissection techniques for the treatment of superficial esophageal cancer and precancerous lesions.BMC gastroenterology · 2025Article
- Single-Cell Sequencing Reveals Heterogeneity and Interactions Between Epithelial Cells and Fibroblasts in Post-ESD Oesophageal Stricture.Journal of cellular and molecular medicine · 2025Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimEndoscopic submucosal dissection (ESD) is used to treat early esophageal cancer and precancerous lesions. Patients undergoing ESD are prone to esophageal stenosis, which impairs therapeutic efficacy and quality of life. This retrospective study aimed to investigate the potential association between patient demographics and esophageal lesion characteristics with the risk of esophageal stenosis following ESD.
methodsFor this retrospective study 190 consecutive patients who underwent ESD between January 2013 and January 2015 were recruited. Data on patient demographics, esophageal lesion-related factors, operation details, esophageal stenosis occurrence and measures taken to prevent or treat stricture were collected, and the normality of distribution of each indicator was assessed with a Kolmogorov-Smirnov test. Stenosis risk factors were then identified using univariate and multivariate logistic regression.
resultsPost-ESD esophageal stenosis occurred in 51 cases. Multivariate logistic regression analysis was performed to identify independent risk factors. A history of EMR/ESD (OR = 4.185, 95% CI: 1.511-11.589), resection circumferential diameter (OR = 1.721, 95% CI: 1.135-2.610), non-en bloc resection (OR = 7.413, 95% CI: 2.398-22.921), submucosal infiltration (OR = 3.449, 95% CI: 1.014-11.734) and circumferential resection range (OR = 57.493, 95% CI: 17.236-191.782) were identified as independent risk factors for post-ESD esophageal stenosis. Spraying porcine fibrin adhesive on the resection bed reduced neither the incidence of postoperative stenosis nor the extent of postoperative dilation.
conclusionPost-ESD esophageal stenosis is significantly related to size and circumferential range of lesion resection. EMR/ESD history, non-en bloc resection and submucosal infiltration may be additional risk factors.
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