Evidence map›Paper›PMID 31953625›Full record

ReviewFish physiology and biochemistry2020

Mechanisms and the role of probiotic Bacillus in mitigating fish pathogens in aquaculture.

Felix K A Kuebutornye, Emmanuel Delwin Abarike, Yishan Lu, Vivian Hlordzi, Michael Essien Sakyi, Gyamfua Afriyie, Zhiwen Wang, Yuan Li, Cai Xia Xie

Abstract readReview
PubMed Publisher
In one paragraph

Review in Fish physiology and biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 189 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. DietaryAnimals : an open access journal from MDPI · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Genomic insights into three Bacillus strains for biocontrol of tobacco black shank disease.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  13. Dietary Encapsulation of a NovelAntioxidants (Basel, Switzerland) · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Felix K A KuebutornyeCollege of Fisheries, Guangdong Ocean University, Huguang Yan East, Zhanjiang, 524088, Guangdong Province, China.
Emmanuel Delwin AbarikeDepartment of Fisheries and Aquatic Resources Management, University for Development Studies, Tamale, Ghana.
Yishan LuCollege of Fisheries, Guangdong Ocean University, Huguang Yan East, Zhanjiang, 524088, Guangdong Province, China. fishdis@163.com.ORCID http://orcid.org/0000-0003-3937-0968
Vivian HlordziLaboratory of Aquatic Animal Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, 524088, Guangdong, China.
Michael Essien SakyiCollege of Fisheries, Guangdong Ocean University, Huguang Yan East, Zhanjiang, 524088, Guangdong Province, China.
Gyamfua AfriyieKey Laboratory of Aquaculture in South China Sea for Aquatic Economic Animal of Guangdong Higher Education Institutes, Fisheries College, Guangdong Ocean University, Zhanjiang, 524025, China.
Zhiwen WangCollege of Fisheries, Guangdong Ocean University, Huguang Yan East, Zhanjiang, 524088, Guangdong Province, China.
Yuan LiCollege of Fisheries, Guangdong Ocean University, Huguang Yan East, Zhanjiang, 524088, Guangdong Province, China.
Cai Xia XieCollege of Fisheries, Guangdong Ocean University, Huguang Yan East, Zhanjiang, 524088, Guangdong Province, China.
Dalian Ocean University · CNGuangdong Ocean University · CNEconomic Research Service · USUniversity for Development Studies · GH

Funding

Shenzhen strategic emerging and future industrial development funds 20170426231005389
6 · The paper itself

Abstract

Diseases are natural components of the environment, and many have economic implications for aquaculture and fisheries. Aquaculture is a fast-growing industry with the aim to meet the high protein demand of the ever-increasing global population; however, the emergence of diseases is a major setback to the industry. Probiotics emerged as a better solution to curb the disease problem in aquaculture among many alternatives. Probiotic Bacillus has been proven to better combat a wide range of fish pathogens relative to other probiotics in aquaculture; therefore, understanding the various mechanisms used by Bacillus in combating diseases will help improve their mode of action hence yielding better results in their combat against pathogens in the aquaculture industry. Thus, an overview of the mechanisms (production of bacteriocins, suppression of virulence gene expression, competition for adhesion sites, production of lytic enzymes, production of antibiotics, immunostimulation, competition for nutrients and energy, and production of organic acids) used by Bacillus probiotics in mitigating fish pathogens ranging from Aeromonas, Vibrio, Streptococcus, Yersinia, Pseudomonas, Clostridium, Acinetobacter, Edwardsiella, Flavobacterium, white spot syndrome virus, and infectious hypodermal and hematopoietic necrosis virus proven to be mitigated by Bacillus have been provided.

Indexed as

BacillusProbioticsAnimalsAquacultureFish DiseasesFishesAquacultureBacillusDiseasesImmunityMechanism

Identifiers

PMID31953625
OpenAlexW2999705714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.