Evidence map›Paper›PMID 31953606›Full record

Observational studyJournal of neurology2020

Complications in cranioplasty after decompressive craniectomy: timing of the intervention.

Taco Goedemans, Dagmar Verbaan, Olivier van der Veer, Maarten Bot, René Post, Jantien Hoogmoed, Michiel B Lequin, Dennis R Buis, W Peter Vandertop, Bert A Coert and 1 more

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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  19. Decompressive craniectomy: A primer for acute care practitioners.Journal of the Intensive Care Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Taco GoedemansAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Dagmar VerbaanAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Olivier van der VeerDepartment of Neurosurgery, Medical Spectrum Twente, Koningsplein 1, 7512 KZ, Enschede, The Netherlands.
Maarten BotAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
René PostAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Jantien HoogmoedAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Michiel B LequinAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Dennis R BuisAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
W Peter VandertopAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Bert A CoertAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Pepijn van den MunckhofAmsterdam Medical Center, Neurosurgical Center Amsterdam, Amsterdam University Medical Centers (UMC), University of Amsterdam, Meibergdreef 9, Room H2-241, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. p.vandenmunckhof@amsterdamumc.nl.
University of Amsterdam · NLAmsterdam University Medical Centers · NLMedisch Spectrum Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo prevent complications following decompressive craniectomy (DC), such as sinking skin flap syndrome, studies suggested early cranioplasty (CP). However, several groups reported higher complication rates in early CP. We studied the clinical characteristics associated with complications in patients undergoing CP, with special emphasis on timing.

methodsA single-center observational cohort study was performed, including all patients undergoing CP from 2006 to 2018, to identify predictors of complications.

results145 patients underwent CP: complications occurred in 33 (23%): 18 (12%) epi/subdural hemorrhage, 10 (7%) bone flap infection, 4 (3%) hygroma requiring drainage, and 1 (1%) post-CP hydrocephalus. On univariate analysis, acute subdural hematoma as etiology of DC, symptomatic cerebrospinal fluid (CSF) flow disturbance (hydrocephalus) prior to CP, and CP within three months after DC were associated with higher complication rates. On multivariate analysis, only acute subdural hematoma as etiology of DC (OR 7.5; 95% CI 1.9-29.5) and symptomatic CSF flow disturbance prior to CP (OR 2.9; 95% CI 1.1-7.9) were associated with higher complication rates. CP performed within three months after DC was not (OR 1.4; 95% CI 0.5-3.9). Pre-CP symptomatic CSF flow disturbance was the only variable associated with the occurrence of epi/subdural hemorrhage. (OR 3.8; 95% CI 1.6-9.0)

conclusionCranioplasty has high complication rates, 23% in our cohort. Contrary to recent systematic reviews, early CP was associated with more complications (41%), explained by the higher incidence of pre-CP CSF flow disturbance and acute subdural hematoma as etiology of DC. CP in such patients should therefore be performed with highest caution.

Indexed as

AdultDecompressive CraniectomyFemaleHumansMaleMiddle AgedPlastic Surgery ProceduresPostoperative ComplicationsRetrospective StudiesSkullCranioplastyDecompressive craniectomyHydrocephalusPostoperative complicationsTiming

Identifiers

PMID31953606
PMCPMC7184041
OpenAlexW3000495136

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.