Evidence map›Paper›PMID 31953560›Full record

ReviewApplied microbiology and biotechnology2020

Novel targets and strategies to combat borreliosis.

Martin Strnad, Libor Grubhoffer, Ryan O M Rego

Open access · bronzeAbstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Current and emerging approaches for eliminatingFrontiers in microbiology · 2024
    Review
  6. Review
  7. Article
  8. Abundance ofInternational journal of environmental research and public health · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Martin StrnadBiology Centre, Institute of Parasitology, Czech Academy of Sciences, Branisovska 31, 37005, Ceske Budejovice, Czech Republic. martin.strnad.cze@gmail.com.ORCID https://orcid.org/0000-0002-1671-6252
Libor GrubhofferBiology Centre, Institute of Parasitology, Czech Academy of Sciences, Branisovska 31, 37005, Ceske Budejovice, Czech Republic.
Ryan O M RegoBiology Centre, Institute of Parasitology, Czech Academy of Sciences, Branisovska 31, 37005, Ceske Budejovice, Czech Republic.
Institute of Parasitology · CZSewanee: The University of the South · USUniversity of South Bohemia in České Budějovice · CZ

Funding

European Union FP7 project ANTIDotE 602272-2Grantová Agentura České Republiky 17-21244S
6 · The paper itself

Abstract

Lyme borreliosis is a bacterial infection that can be spread to humans by infected ticks and may severely affect many organs and tissues. Nearly four decades have elapsed since the discovery of the disease agent called Borrelia burgdorferi. Although there is a plethora of knowledge on the infectious agent and thousands of scientific publications, an effective way on how to combat and prevent Lyme borreliosis has not been found yet. There is no vaccine for humans available, and only one active vaccine program in clinical development is currently running. A spirited search for possible disease interventions is of high public interest as surveillance data indicates that the number of cases of Lyme borreliosis is steadily increasing in Europe and North America. This review provides a condensed digest of the history of vaccine development up to new promising vaccine candidates and strategies that are targeted against Lyme borreliosis, including elements of the tick vector, the reservoir hosts, and the Borrelia pathogen itself.

Indexed as

AnimalsBacterial VaccinesBorrelia burgdorferiDisease VectorsHumansLyme DiseaseTicksBacterial VaccinesAnti-tick strategiesHuman pathogenLyme borreliosisPublic healthVaccine candidates

Identifiers

PMID31953560
PMCPMC7222997
OpenAlexW3000377922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.