Evidence map›Paper›PMID 31953534›Full record

ArticleNature immunology2020

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8

Sarah L Hayward, Christopher D Scharer, Emily K Cartwright, Shiki Takamura, Zheng-Rong Tiger Li, Jeremy M Boss, Jacob E Kohlmeier

Open access · bronzeAbstract read
In one paragraph

Article in Nature immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. CD8MedComm · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. A variational deep-learning approach to modeling memory T cell dynamics.bioRxiv : the preprint server for biology · 2025
    Article
  16. Article
  17. Review
  18. Waning immunity drives respiratory virus evolution and reinfection.Evolution, medicine, and public health · 2025
    Article
  19. Eating for immunity: how diet shapes our defenses.Current opinion in immunology · 2024
    Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sarah L Hayward *Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0001-7052-5556
Christopher D Scharer *Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0001-7716-8504
Emily K CartwrightDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Shiki TakamuraDepartment of Immunology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Zheng-Rong Tiger LiDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Jeremy M BossDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-2432-1840
Jacob E KohlmeierDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. jkohlmeier@emory.edu.ORCID http://orcid.org/0000-0002-7209-6641
Emory University · USKindai University · JP

Funding

Regulation of Pathogenic Plasma Cells in Human SLEP01AI125180 · NIAID · EMORY UNIVERSITY · PI Ignacio E. Sanz · 2016 to 2026
$28.2M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM008490 · NIGMS · EMORY UNIVERSITY · PI BOSS, JEREMY M. · 1993 to 2022
$8.0M
Regulation of PD-1 gene expressionR01AI113021 · NIAID · EMORY UNIVERSITY · PI BOSS, JEREMY M. · 2014 to 2024
$4.7M
A Model System for the Study of Human B-cell ToleranceR37AI049660 · NIAID · UNIVERSITY OF ROCHESTER · PI SANZ, IGNACIO E. · 2010 to 2019
$3.7M
Imprinting of Lung-Resident T Cell MemoryR01HL122559 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2015 to 2019
$1.9M
Regulation of lung TRM maintenance and the decline of pulmonary cellular immunityR01HL138508 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2017 to 2019
$1.2M
Identifying mechanisms of lung tissue-resident memory CD8 T cell decayF31HL136101 · NHLBI · EMORY UNIVERSITY · PI HAYWARD, SARAH LOUISE · 2017 to 2019
$110k
NHLBI NIH HHS F31 HL136101NHLBI NIH HHS R01 HL122559NHLBI NIH HHS R01 HL138508NIAID NIH HHS HHSN272201300006CNIAID NIH HHS HHSN272201400004CNIAID NIH HHS P01 AI125180NIAID NIH HHS R01 AI113021NIAID NIH HHS R37 AI049660NIGMS NIH HHS T32 GM008490
6 · The paper itself

Abstract

Tissue-resident memory T cells (T

Indexed as

AnimalsApoptosisCD8-Positive T-LymphocytesCell SurvivalCellular MicroenvironmentCellular ReprogrammingEpigenesis, GeneticFemaleImmunologic MemoryLungMaleMiceMice, Inbred C57BLOrthomyxoviridae Infections

Identifiers

PMID31953534
PMCPMC7044042
OpenAlexW3000094117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.