Evidence map›Paper›PMID 31953372›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Vaporized Cannabis Extracts Have Reinforcing Properties and Support Conditioned Drug-Seeking Behavior in Rats.

Timothy G Freels, Lydia N Baxter-Potter, Janelle M Lugo, Nicholas C Glodosky, Hayden R Wright, Samantha L Baglot, Gavin N Petrie, Zhihao Yu, Brian H Clowers, Carrie Cuttler and 3 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 117 citations in OpenAlex.

  1. Review
  2. Article
  3. Identifying behavioral and biological predictors of cannabis vapor self-administration in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models.Current topics in behavioral neurosciences · 2026
    Review
  8. Cannabis produces acute hyperphagia in humans and rodents via increased reward valuation for, and motivation to, acquire food.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Transgenerational effects of perinatal cannabis exposure on female reproductive parameters in mice.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  11. Article
  12. Review
  13. Cannabis use disorder: from neurobiology to treatment.The Journal of clinical investigation · 2024
    Review
  14. Review
  15. Article
  16. Adult Consequences of Repeated Nicotine Vapor Inhalation in Adolescent Rats.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  17. The Developmental Trajectory to Cannabis Use Disorder.The American journal of psychiatry · 2024
    Article
  18. Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Timothy G FreelsDepartments of Integrative Physiology and Neuroscience.ORCID 0000-0002-8212-0844
Lydia N Baxter-PotterDepartments of Integrative Physiology and Neuroscience.
Janelle M LugoDepartments of Integrative Physiology and Neuroscience.
Nicholas C GlodoskyPsychology.ORCID 0000-0001-6098-3465
Hayden R WrightDepartments of Integrative Physiology and Neuroscience.ORCID 0000-0002-9749-2405
Samantha L BaglotDepartments of Cell Biology and Anatomy and Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada.ORCID 0000-0001-8898-2122
Gavin N PetrieDepartments of Cell Biology and Anatomy and Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
Zhihao YuChemistry, Washington State University, Pullman, Washington 99164, and.
Brian H ClowersChemistry, Washington State University, Pullman, Washington 99164, and.ORCID 0000-0002-5809-9379
Carrie CuttlerPsychology.ORCID 0000-0002-5890-2985
Rita A FuchsDepartments of Integrative Physiology and Neuroscience.ORCID 0000-0002-5999-9969
Matthew N HillDepartments of Cell Biology and Anatomy and Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
Ryan J McLaughlinDepartments of Integrative Physiology and Neuroscience, ryan.mclaughlin@wsu.edu.ORCID 0000-0002-2875-0685
Laboratoire d’immunologie intégrative du cancer · FRChicago Neuropsychology Group · USUniversity of Calgary · CAWashington State University · US

Funding

Drug Context-Induced Instrumental Cocaine Seeking: Influence of Memory ReconsolidR01DA025646 · NIDA · WASHINGTON STATE UNIVERSITY · PI FUCHS LOKENSGARD, RITA A · 2010 to 2021
$3.5M
Effects of developmental cannabis exposure on prefrontocortical structure and functionR21DA043722 · NIDA · WASHINGTON STATE UNIVERSITY · PI MCLAUGHLIN, RYAN JOSEPH · 2017 to 2018
$421k
CIHRNIDA NIH HHS R01 DA025646NIDA NIH HHS R21 DA043722
6 · The paper itself

Abstract

Recent trends in cannabis legalization have increased the necessity to better understand the effects of cannabis use. Animal models involving traditional cannabinoid self-administration approaches have been notoriously difficult to establish and differences in the drug used and its route of administration have limited the translational value of preclinical studies. To address this challenge in the field, we have developed a novel method of cannabis self-administration using response-contingent delivery of vaporized Δ

Indexed as

CannabisReinforcement, PsychologyAnimalsBrainConditioning, OperantDronabinolDrug-Seeking BehaviorEatingEnergy MetabolismHallucinogensLocomotionMaleMarijuana SmokingPlant ExtractsRatsRats, Sprague-DawleyDronabinolHallucinogensPlant ExtractsReceptor, Cannabinoid, CB1cannabinoidcannabisratself-administrationtranslationalvapor

Identifiers

PMID31953372
PMCPMC7046447
OpenAlexW2998829304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.