Evidence map›Paper›PMID 31953354›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

IL-1 Transcriptional Responses to Lipopolysaccharides Are Regulated by a Complex of RNA Binding Proteins.

Lihua Shi, Li Song, Kelly Maurer, Ying Dou, Vishesh R Patel, Chun Su, Michelle E Leonard, Sumei Lu, Kenyaita M Hodge, Annabel Torres and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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  8. Review
  9. Article
  10. Chromatin Modifications in 22q11.2 Deletion Syndrome.Journal of clinical immunology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Lihua ShiDivision of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Li SongDivision of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Kelly MaurerDivision of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Ying DouDivision of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Vishesh R PatelDivision of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Chun SuCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.ORCID 0000-0001-6388-8666
Michelle E LeonardCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Sumei LuCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.ORCID 0000-0002-5490-3884
Kenyaita M HodgeCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Annabel TorresDivision of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Alessandra ChesiCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.ORCID 0000-0002-0954-7446
Struan F A GrantCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.ORCID 0000-0003-2025-5302
Andrew D WellsCenter for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Zhe ZhangDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104; and.
Michelle A PetriDivision of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.ORCID 0000-0003-1441-5373
Kathleen E SullivanDivision of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104; sullivank@email.chop.edu.ORCID 0000-0003-4018-1646
Children's Hospital of Philadelphia · USJohns Hopkins University · US

Funding

Hopkins Lupus CohortR01AR069572 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI PETRI, MICHELLE A · 2016 to 2020
$3.4M
Network-based algorithms for target identification and drug repositioning from genetic associationsR01HG010067 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI GREENE, CASEY S · 2018 to 2022
$3.2M
Epigenetic imprinting of follicular helper T cell fate and function in lupusR01AI123539 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LAUFER, TERRI M. · 2017 to 2020
$3.1M
Treating chronic viral infection by epigenetic reprogramming of exhausted CD8 T cellsR01AI130115 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABT, MICHAEL C. · 2017 to 2021
$2.7M
Epigenomics of SLER01AR058547 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI SULLIVAN, KATHLEEN E · 2009 to 2013
$1.8M
NHGRI NIH HHS R01 HG010067NIAID NIH HHS R01 AI123539NIAID NIH HHS R01 AI130115NIAMS NIH HHS R01 AR058547NIAMS NIH HHS R01 AR069572
6 · The paper itself

Abstract

The

Indexed as

Transcription, GeneticCell LineE1A-Associated p300 ProteinHumansInterleukin-1alphaInterleukin-1betaInterleukin 1 Receptor Antagonist ProteinLipopolysaccharidesMonocytesRNA-Binding ProteinsE1A-Associated p300 ProteinEP300 protein, humanIL1A protein, humanIL1B protein, humanIL1RN protein, humanInterleukin-1alphaInterleukin-1betaInterleukin 1 Receptor Antagonist ProteinLipopolysaccharidesRNA-Binding Proteins

Identifiers

PMID31953354
PMCPMC7033021
OpenAlexW2999546534

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.