Evidence map›Paper›PMID 31953347›Full record

ArticleGenome research2020

A

Lei Zhang, Anshun He, Bohan Chen, Jinfang Bi, Jun Chen, Dianhao Guo, Yuyang Qian, Wenbin Wang, Tengfei Shi, Zhongfang Zhao and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  11. The multifaceted functions of long non-coding RNAExpert reviews in molecular medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Lei Zhang *State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Anshun He *State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Bohan ChenState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Jinfang BiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Jun ChenState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Dianhao GuoState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Yuyang QianState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Wenbin WangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Tengfei ShiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Zhongfang ZhaoState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Jiandang ShiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Woojin AnDepartment of Biochemistry and Molecular Medicine, Norris Cancer Center, University of Southern California, Los Angeles, California 90033, USA.
Frank AttenelloKeck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
Wange LuState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, 300071, Tianjin, China.
Nankai University · CNUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temozolomide (TMZ) is a frequently used chemotherapy for glioma; however, chemoresistance is a major problem limiting its effectiveness. Thus, knowledge of mechanisms underlying this outcome could improve patient prognosis. Here, we report that deletion of a regulatory element in the

Indexed as

Antineoplastic Agents, AlkylatingBase SequenceCalcium-Binding ProteinsCarrier ProteinsCell Line, TumorCell ProliferationCell SurvivalCRISPR-Cas SystemsDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticGene Regulatory NetworksGliomaHumansNeoplasm ProteinsRNA, Long NoncodingTemozolomideAntineoplastic Agents, AlkylatingCalcium-Binding ProteinsCALCOCO1 protein, humanCarrier ProteinsHOTAIR long untranslated RNA, humanNeoplasm ProteinsRNA, Long NoncodingTemozolomideTranscription FactorsZC3H10 protein, human

Identifiers

PMID31953347
PMCPMC7050528
OpenAlexW3000337827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.