Evidence map›Paper›PMID 31953340›Full record

ArticleApplied and environmental microbiology2020

Site-Specific Profiling of the Dental Mycobiome Reveals Strong Taxonomic Shifts during Progression of Early-Childhood Caries.

Lauren M O'Connell, Ryan Santos, Garrett Springer, Robert A Burne, Marcelle M Nascimento, Vincent P Richards

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. AJournal of bacteriology · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Microorganisms · 2025
    Review
  12. Interactions between non-Journal of oral microbiology · 2025
    Article
  13. The Oral Microbiome: A Key Determinant of Oral Health.Advances in experimental medicine and biology · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Oral Mycobiota: A Narrative Review.Dentistry journal · 2024
    Review
  18. Review
  19. Unveiling the complexity of early childhood caries:Journal of oral microbiology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lauren M O'ConnellDepartment of Biological Sciences, College of Science, Clemson University, Clemson, South Carolina, USA.
Ryan SantosDepartment of Biological Sciences, College of Science, Clemson University, Clemson, South Carolina, USA.
Garrett SpringerDepartment of Biological Sciences, College of Science, Clemson University, Clemson, South Carolina, USA.
Robert A BurneDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-4234-0316
Marcelle M NascimentoDepartment of Restorative Dental Sciences, Division of Operative Dentistry, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Vincent P RichardsDepartment of Biological Sciences, College of Science, Clemson University, Clemson, South Carolina, USA vpricha@clemson.edu.ORCID 0000-0002-9309-6595
Clemson University · USUniversity of Florida · US

Funding

Probiotics that moderate pH and antagonize pathogens to promote oral healthR01DE025832 · NIDCR · UNIVERSITY OF FLORIDA · PI BURNE, ROBERT A · 2016 to 2020
$3.4M
NIDCR NIH HHS R01 DE025832
6 · The paper itself

Abstract

Dental caries is one of the most common diseases worldwide. Bacteria and fungi are both commensals in the oral cavity; however, most research regarding caries has focused on bacterial impacts. The oral fungal mycobiome associated with caries is not well characterized, and its role in disease is unclear. ITS1 amplicon sequencing was used to generate taxonomic profiles from site-specific supragingival plaque samples (

Indexed as

Disease ProgressionMycobiomeChildChild, PreschoolDental CariesFungiHumansMouthamplicondental cariesfungiITSmicrobiomemycobiomeoraloral microbiology

Identifiers

PMID31953340
PMCPMC7082576
OpenAlexW3002183889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.