Evidence map›Paper›PMID 31953336›Full record

ArticleApplied and environmental microbiology2020

GlnR Negatively Regulates Glutamate-Dependent Acid Resistance in Lactobacillus brevis.

Luchan Gong, Cong Ren, Yan Xu

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Role ofFoods (Basel, Switzerland) · 2025
    Article
  5. Article
  6. A new paradigm for the regulation of A40926B0 biosynthesis.Synthetic and systems biotechnology · 2025
    Article
  7. Enhancing Monacolin K and GABA Biosynthesis inJournal of fungi (Basel, Switzerland) · 2025
    Article
  8. GlnR positively affects the acid resistance ofFrontiers in microbiology · 2025
    Article
  9. Article
  10. Article
  11. Glutamine synthetase and GlnR regulate nitrogen metabolism inApplied and environmental microbiology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Development and Applications of CRISPR/Cas9-Based Genome Editing inInternational journal of molecular sciences · 2022
    Review
  16. Cysteine protected cells from HWorld journal of microbiology & biotechnology · 2022
    Article
  17. Article
  18. Article
  19. Volatile Organic Compound-Mediated Antifungal Activity ofApplied and environmental microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Luchan GongKey Laboratory of Industrial Biotechnology of Ministry of Education, State Key Laboratory of Food Science and Technology, School of Biotechnology, Jiangnan University, Wuxi, China.
Cong RenKey Laboratory of Industrial Biotechnology of Ministry of Education, State Key Laboratory of Food Science and Technology, School of Biotechnology, Jiangnan University, Wuxi, China congren@jiangnan.edu.cn yxu@jiangnan.edu.cn.
Yan XuKey Laboratory of Industrial Biotechnology of Ministry of Education, State Key Laboratory of Food Science and Technology, School of Biotechnology, Jiangnan University, Wuxi, China congren@jiangnan.edu.cn yxu@jiangnan.edu.cn.
Jiangnan University · CNState Key Laboratory of Food Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid bacteria often encounter a variety of multiple stresses in their natural and industrial fermentation environments. The glutamate decarboxylase (GAD) system is one of the most important acid resistance systems in lactic acid bacteria. In this study, we demonstrated that GlnR, a nitrogen regulator in Gram-positive bacteria, directly modulated γ-aminobutyric acid (GABA) conversion from glutamate and was involved in glutamate-dependent acid resistance in

Indexed as

AcidsBacterial ProteinsGlutamic AcidLevilactobacillus brevisTrans-ActivatorsAcidsBacterial ProteinsGlutamic AcidTrans-Activatorsacid stressGABAGlnRglutamate-dependent acid resistanceLactobacillus brevisγ-aminobutyric acid

Identifiers

PMID31953336
PMCPMC7082588
OpenAlexW2998906233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.