Evidence map›Paper›PMID 31953235›Full record

ReviewThe Journal of hospital infection2020

Imaging in the investigation and management of Staphylococcus aureus bacteraemia: a role for advanced imaging techniques.

A L Goodman, G J Cook, V Goh

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of hospital infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Diagnostic Challenges in Sepsis.Current infectious disease reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

A L GoodmanMRC Clinical Trials Unit, London, UK; Centre for Clinical Infection and Diagnostics Research, King's College London, Guy's and St Thomas' NHS Foundation Trust, London, UK. Electronic address: anna.goodman@ucl.ac.uk.
G J CookCancer Imaging Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; The King's College London, Guys & St Thomas' PET Centre, London, UK.
V GohCancer Imaging Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Radiology, Guy's & St Thomas' Hospitals NHS Foundation Trust, London, UK.
King's College London · GB

Funding

Cancer Research UK 16463Department of Health NIHR133719Medical Research Council MC_UU_12023/22Wellcome Trust 203148
6 · The paper itself

Abstract

Staphylococcus aureus bacteraemia (SAB) continues to affect ∼25,000 patients in the UK per year with a high crude mortality of 30% at 90 days. Prompt source control improves outcomes in sepsis and SAB and is included in sepsis guidelines. A recent clinical trial of adjunctive antibiotic treatment in SAB found that the majority of recurrences of SAB were associated with a failure of source management. In this condition, the ability to control the source of infection may be limited by the ability to detect a focus of infection. Echocardiogram is now a routinely used tool to detect such unknown foci in the form of unexpected infectious vegetations. We review the literature to explore the utility of advanced imaging techniques, such as [18F]fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and magnetic resonance imaging (including whole-body MRI), to detect foci which may otherwise be missed. As unknown foci are associated with increased mortality, we propose that increasing the detection of foci could enable improved source control and result in improved outcomes in SAB.

Indexed as

Disease ManagementAnti-Bacterial AgentsBacteremiaDiagnostic ImagingEchocardiographyHumansPositron Emission Tomography Computed TomographyStandard of CareStaphylococcal InfectionsUnited KingdomAnti-Bacterial AgentsComputed tomographyDiagnostic imagingFocus of infectionMagnetic resonance imagingPositron emission tomographyStandard of careStaphylococcus aureus bacteraemia

Identifiers

PMID31953235
PMCPMC7616165
OpenAlexW3000508209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.